Khaziakhmetova V N, Ziganshina L E
Eksp Klin Farmakol. 2012;75(11):38-43.
The review presents comparative description of anti-inflammatory effects of antidepressants from various classes studied on carrageenan- and formalin-induced paw edema in rats. The role of the central and peripheral components in the mechanisms of anti-inflammatory activity and the drug effects on production of mediators and modulators of inflammation is discussed.
该综述介绍了各类抗抑郁药对大鼠角叉菜胶和福尔马林诱导的爪肿胀抗炎作用的比较描述。讨论了中枢和外周成分在抗炎活性机制中的作用以及药物对炎症介质和调节剂产生的影响。
