血管并发症妊娠后的亚临床甲状腺功能减退
Subclinical hypothyroidism after vascular complicated pregnancy.
作者信息
van der Zanden Moniek, Hop-de Groot Rianne J, Sweep Fred C G J, Ross H Alec, den Heijer Martin, Spaanderman Marc E A
机构信息
Department of Obstetrics and Gynaecology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.
出版信息
Hypertens Pregnancy. 2013;32(1):1-10. doi: 10.3109/10641955.2011.642435. Epub 2013 Jan 16.
OBJECTIVE
Women with a history of vascular complicated pregnancy are at risk for developing remote cardiovascular disease. It is associated with underlying cardiovascular risk factors both jeopardizing trophoblast and vascular function. Subclinical hypothyroidism may relate to both conditions.
METHODS
In 372 women with a history of vascular complicated pregnancy, we assessed thyroid function.
RESULTS
Subclinical hypothyroidism was diagnosed in 73/372 women (19.6%). It occurred more often when pregnancy ended before 32 weeks of gestation (p = 0.008).
CONCLUSION
In this cohort, subclinical hypothyroidism is more common after very preterm delivery. It may contribute to the elevated risk of remote cardiovascular disease.
目的
有血管并发症妊娠史的女性有发生远期心血管疾病的风险。这与潜在的心血管危险因素相关，这些因素会危及滋养层和血管功能。亚临床甲状腺功能减退可能与这两种情况都有关。
方法
在372例有血管并发症妊娠史的女性中，我们评估了甲状腺功能。
结果
73/372例女性（19.6%）被诊断为亚临床甲状腺功能减退。当妊娠在妊娠32周前结束时，其发生频率更高（p = 0.008）。
结论
在这个队列中，亚临床甲状腺功能减退在极早产之后更常见。它可能导致远期心血管疾病风险升高。
Zotero 插件