肝纤维化消退过程中肌成纤维细胞的失活 - Suppr

Suppr

超能文献

Inactivation of myofibroblasts during regression of liver fibrosis.

作者信息

Kisseleva Tatiana, Brenner David A

出版信息

Cell Cycle. 2013 Feb 1;12(3):381-2. doi: 10.4161/cc.23549. Epub 2013 Jan 16.

DOI:10.4161/cc.23549

PMID:23324345

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3587431/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2240/3587431/2df3f9a7f0f5/cc-12-381-g1.jpg

相似文献

Inactivation of myofibroblasts during regression of liver fibrosis.肝纤维化消退过程中肌成纤维细胞的失活

Cell Cycle. 2013 Feb 1;12(3):381-2. doi: 10.4161/cc.23549. Epub 2013 Jan 16.

Peroxisome proliferator-activated receptor gamma inhibits hepatic fibrosis in rats.过氧化物酶体增殖物激活受体γ抑制大鼠肝纤维化。

Hepatobiliary Pancreat Dis Int. 2011 Feb;10(1):64-71. doi: 10.1016/s1499-3872(11)60009-x.

Single Cell RNA Sequencing Identifies Subsets of Hepatic Stellate Cells and Myofibroblasts in Liver Fibrosis.单细胞 RNA 测序鉴定肝纤维化中肝星状细胞和肌成纤维细胞亚群。

Cells. 2019 May 24;8(5):503. doi: 10.3390/cells8050503.

Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis.肌成纤维细胞在肝纤维化消退过程中会恢复为非激活表型。

Proc Natl Acad Sci U S A. 2012 Jun 12;109(24):9448-53. doi: 10.1073/pnas.1201840109. Epub 2012 May 7.

Hedgehog-YAP Signaling Pathway Regulates Glutaminolysis to Control Activation of Hepatic Stellate Cells.刺猬-YAP 信号通路调控谷氨酰胺代谢以控制肝星状细胞的激活。

Gastroenterology. 2018 Apr;154(5):1465-1479.e13. doi: 10.1053/j.gastro.2017.12.022. Epub 2018 Jan 3.

Cytoglobin is expressed in hepatic stellate cells, but not in myofibroblasts, in normal and fibrotic human liver.在正常和纤维化的人肝组织中，细胞球蛋白仅在肝星状细胞中表达，而不在肌成纤维细胞中表达。

Lab Invest. 2014 Feb;94(2):192-207. doi: 10.1038/labinvest.2013.135. Epub 2013 Dec 2.

Hedgehog controls hepatic stellate cell fate by regulating metabolism.刺猬通过调节代谢控制肝星状细胞命运。

Gastroenterology. 2012 Nov;143(5):1319-1329.e11. doi: 10.1053/j.gastro.2012.07.115. Epub 2012 Aug 8.

Molecular interplays in hepatic stellate cells: apoptosis, senescence, and phenotype reversion as cellular connections that modulate liver fibrosis.肝星状细胞中的分子相互作用：细胞凋亡、衰老以及表型逆转作为调节肝纤维化的细胞关联机制

Cell Biol Int. 2017 Sep;41(9):946-959. doi: 10.1002/cbin.10790. Epub 2017 Jul 20.

P300 Acetyltransferase Mediates Stiffness-Induced Activation of Hepatic Stellate Cells Into Tumor-Promoting Myofibroblasts.P300 乙酰转移酶介导肝星状细胞硬度诱导激活为促肿瘤肌成纤维细胞。

Gastroenterology. 2018 Jun;154(8):2209-2221.e14. doi: 10.1053/j.gastro.2018.02.015. Epub 2018 Feb 15.

Liver fibrosis in elderly cadavers: localization of collagen types I, III, and IV, α-smooth muscle actin, and elastic fibers.老年尸体的肝纤维化：胶原 I、III、IV 型、α-平滑肌肌动蛋白和弹性纤维的定位。

Anat Rec (Hoboken). 2012 Jul;295(7):1159-67. doi: 10.1002/ar.22504. Epub 2012 May 30.

引用本文的文献

Liver Fibrosis Leading to Cirrhosis: Basic Mechanisms and Clinical Perspectives.肝纤维化导致肝硬化：基本机制与临床展望。

Biomedicines. 2024 Sep 30;12(10):2229. doi: 10.3390/biomedicines12102229.

Hepatic Fibrosis and Cancer: The Silent Threats of Metabolic Syndrome.代谢综合征：肝纤维化和癌症的沉默威胁。

Diabetes Metab J. 2024 Mar;48(2):161-169. doi: 10.4093/dmj.2023.0240. Epub 2024 Jan 26.

Regulators, functions, and mechanotransduction pathways of matrix stiffness in hepatic disease.肝病中基质硬度的调节因子、功能及机械转导途径

Front Physiol. 2023 Jan 12;14:1098129. doi: 10.3389/fphys.2023.1098129. eCollection 2023.

Molecular and cellular mechanisms of liver fibrosis and its regression.肝纤维化及其逆转的分子和细胞机制。

Nat Rev Gastroenterol Hepatol. 2021 Mar;18(3):151-166. doi: 10.1038/s41575-020-00372-7. Epub 2020 Oct 30.

RelB promotes liver fibrosis via inducing the release of injury-associated inflammatory cytokines.RelB 通过诱导损伤相关的炎症细胞因子释放促进肝纤维化。

J Cell Mol Med. 2020 Jun;24(11):6008-6014. doi: 10.1111/jcmm.15108. Epub 2020 Apr 19.

Mechanisms of Fibrosis Development in Nonalcoholic Steatohepatitis.非酒精性脂肪性肝炎纤维化发展的机制。

Gastroenterology. 2020 May;158(7):1913-1928. doi: 10.1053/j.gastro.2019.11.311. Epub 2020 Feb 8.

Matrix Mechanics as Regulatory Factors and Therapeutic Targets in Hepatic Fibrosis.基质力学作为肝纤维化的调控因子和治疗靶点。

Int J Biol Sci. 2019 Sep 7;15(12):2509-2521. doi: 10.7150/ijbs.37500. eCollection 2019.

Chemically modified liposomes carrying TRAIL target activated hepatic stellate cells and ameliorate hepatic fibrosis in vitro and in vivo.携带 TRAIL 的化学修饰脂质体靶向激活的肝星状细胞，并在体内外改善肝纤维化。

J Cell Mol Med. 2019 Mar;23(3):1951-1962. doi: 10.1111/jcmm.14097. Epub 2018 Dec 27.

Gulf war illness-related chemicals increase CD11b/c monocyte infiltration into the liver and aggravate hepatic cholestasis in a rodent model.海湾战争相关化学物质增加 CD11b/c 单核细胞浸润肝脏，并在啮齿动物模型中加重肝内胆汁淤积。

Sci Rep. 2018 Sep 3;8(1):13147. doi: 10.1038/s41598-018-31599-9.

Quantitative Proteomic analysis on Activated Hepatic Stellate Cells reversion Reveal STAT1 as a key regulator between Liver Fibrosis and recovery.定量蛋白质组学分析激活的肝星状细胞逆转揭示 STAT1 是肝纤维化和恢复之间的关键调节因子。

Sci Rep. 2017 Mar 21;7:44910. doi: 10.1038/srep44910.

本文引用的文献

Deactivation of hepatic stellate cells during liver fibrosis resolution in mice.在小鼠肝纤维化消退过程中肝星状细胞的失活。

Gastroenterology. 2012 Oct;143(4):1073-83.e22. doi: 10.1053/j.gastro.2012.06.036. Epub 2012 Jun 27.

Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis.肌成纤维细胞在肝纤维化消退过程中会恢复为非激活表型。

Proc Natl Acad Sci U S A. 2012 Jun 12;109(24):9448-53. doi: 10.1073/pnas.1201840109. Epub 2012 May 7.

Myofibroblast - like cells and liver fibrogenesis: Emerging concepts in a rapidly moving scenario.肌成纤维细胞样细胞与肝纤维化：快速发展背景下的新观念

Mol Aspects Med. 2008 Feb-Apr;29(1-2):58-66. doi: 10.1016/j.mam.2007.09.002. Epub 2007 Oct 7.

Hepatic stellate cells and the reversal of fibrosis.肝星状细胞与肝纤维化的逆转

J Gastroenterol Hepatol. 2006 Oct;21 Suppl 3:S84-7. doi: 10.1111/j.1440-1746.2006.04584.x.

Adipogenic phenotype of hepatic stellate cells.肝星状细胞的脂肪生成表型

Alcohol Clin Exp Res. 2005 Nov;29(11 Suppl):132S-133S. doi: 10.1097/01.alc.0000189279.92602.f0.

Antiapoptotic and anti-inflammatory mechanisms of heat-shock protein protection.热休克蛋白保护的抗凋亡和抗炎机制。

Ann N Y Acad Sci. 2005 Aug;1053:74-83. doi: 10.1196/annals.1344.007.

Liver fibrosis.肝纤维化

J Clin Invest. 2005 Feb;115(2):209-18. doi: 10.1172/JCI24282.

Adipogenic transcriptional regulation of hepatic stellate cells.肝星状细胞的脂肪生成转录调控

J Biol Chem. 2005 Feb 11;280(6):4959-67. doi: 10.1074/jbc.M410078200. Epub 2004 Nov 9.

Mechanisms of spontaneous resolution of rat liver fibrosis. Hepatic stellate cell apoptosis and reduced hepatic expression of metalloproteinase inhibitors.大鼠肝纤维化自发消退的机制。肝星状细胞凋亡及金属蛋白酶抑制剂肝表达降低。

J Clin Invest. 1998 Aug 1;102(3):538-49. doi: 10.1172/JCI1018.

Hepatic lipocytes: the principal collagen-producing cells of normal rat liver.肝星状细胞：正常大鼠肝脏中主要的胶原生成细胞。

Proc Natl Acad Sci U S A. 1985 Dec;82(24):8681-5. doi: 10.1073/pnas.82.24.8681.

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验