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急性 B 型主动脉夹层破裂行急诊手术的临床疗效。

Clinical outcomes of emergency surgery for acute type B aortic dissection with rupture.

机构信息

Cardiovascular Center, Yokohama City University Medical Center, Yokohama, Kanagawa, Japan.

出版信息

Eur J Cardiothorac Surg. 2013 Aug;44(2):360-4; discussion 364-5. doi: 10.1093/ejcts/ezs703. Epub 2013 Jan 16.

Abstract

OBJECTIVES

The purpose of this study was to evaluate the clinical outcomes of emergency surgery for acute type B aortic dissection with rupture and to compare results between open surgery and thoracic endovascular aortic repair (TEVAR).

METHODS

Two hundred and ninety-four patients with acute type B aortic dissection were admitted to our hospital between January 2000 and March 2012. At presentation, 30 (10%) patients had rupture (20 men, 10 women; mean age, 71 ± 15 years), among whom 23 underwent emergency surgery: 9 underwent TEVAR and 14 underwent open surgery. The objective of TEVAR was closure of the primary entry site and the secondary tear site in the descending thoracic aorta.

RESULTS

In the TEVAR group, technical success was achieved: the primary entry site was closed, and bleeding was controlled in all 9 patients. There was no operative death, and 1 (13%) patient had cerebral infarction. In the open surgery group, 2 (14%) patients died during hospitalization, and 4 (29%) had cerebral infarction in the acute phase. Hospitalization tended to be longer in the open surgery group than in the TEVAR group. The overall survival rate at 1 year was 71 ± 17% in the TEVAR group and 86 ± 9% in the open surgery group (P = 0.89).

CONCLUSIONS

TEVAR for acute type B aortic dissection with rupture could be performed with relatively low morbidity and mortality, with no significant difference when compared with open surgery. The main objective of TEVAR for acute type B aortic dissection with rupture is control of bleeding, which can be achieved by closing the primary entry site and the secondary tear site in the descending thoracic aorta. If anatomically feasible and performed immediately, TEVAR is the treatment of choice for acute type B aortic dissection with rupture because it is less invasive than open surgery.

摘要

目的

本研究旨在评估急性 B 型主动脉夹层破裂行急诊手术的临床结果,并比较开放手术与胸主动脉腔内修复术(TEVAR)的结果。

方法

2000 年 1 月至 2012 年 3 月期间,我院收治了 294 例急性 B 型主动脉夹层患者。就诊时,30 例(10%)患者发生破裂(20 例男性,10 例女性;平均年龄 71 ± 15 岁),其中 23 例行急诊手术:9 例行 TEVAR,14 例行开放手术。TEVAR 的目的是封闭降主动脉的原发破口和继发撕裂口。

结果

TEVAR 组技术成功率为 100%:9 例患者的原发破口封闭,出血得到控制。无手术死亡病例,1 例(13%)患者发生脑梗死。开放手术组 2 例(14%)患者住院期间死亡,4 例(29%)患者在急性期发生脑梗死。开放手术组的住院时间较 TEVAR 组长。TEVAR 组 1 年总生存率为 71 ± 17%,开放手术组为 86 ± 9%(P = 0.89)。

结论

急性 B 型主动脉夹层破裂行 TEVAR 治疗的发病率和死亡率相对较低,与开放手术相比无显著差异。急性 B 型主动脉夹层破裂行 TEVAR 的主要目的是控制出血,可以通过封闭降主动脉的原发破口和继发撕裂口来实现。如果解剖结构可行且立即进行,TEVAR 是急性 B 型主动脉夹层破裂的首选治疗方法,因为它比开放手术创伤更小。

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