van den Berg Neeltje, Meinke-Franze Claudia, Fiss Thomas, Hoffmann Wolfgang
Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.
Blood Press Monit. 2013 Apr;18(2):63-71. doi: 10.1097/MBP.0b013e32835d1002.
The AGnES-concept (GP-supporting, community-based, e-health-assisted, systemic intervention) includes the delegation of general practitioner (GP)-home visits to qualified practice assistants, especially in underserved areas. Most visited patients were elderly, multimorbid patients with limited mobility. We analyzed a subgroup of hypertension patients to assess the proportion of patients with controlled hypertension, the number of patients that changed between different categories of blood pressure during the project, and to identify possible determinants for these changes.
Eligible patients were selected by the participating GPs. Hypertensive patients with at least two blood pressure measurements were included. Two-level mixed-effects multiple binary logistic regression analyses were conducted to evaluate possible determinants for the found effects.
Overall, 776 patients (mean age 79.2 years; SD 8.1 years; range 38-98 years) were included in the analysis. During the project, the mean values for systolic (from 136.1 to 131.0 mmHg, P<0.0001) and diastolic (from 77.0 to 75.7 mmHg, P=0.0026) blood pressure decreased. In 26.0% of the patients there was a change from hypertensive blood pressure values to normotensive values and vice versa in 14.3% (P<0.0001). Multilevel regression models did not show single elements of the complex intervention as determinants for changing to normotensive blood pressure values.
Although the study was conducted under real life conditions and therefore had some methodological limitations, the delegation of home visits to qualified practice assistants may have had a positive influence on changes of blood pressure with elderly hypertension patients. The study population represents a relevant population for medical care, which might benefit from the implementation of the AGnES-concept.
AGnES概念(全科医生支持、基于社区、电子健康辅助、系统干预)包括将全科医生(GP)家访工作委托给合格的执业助理,特别是在服务不足的地区。大多数家访患者是行动不便的老年多病患者。我们分析了一组高血压患者,以评估血压得到控制的患者比例、项目期间不同血压类别之间变化的患者数量,并确定这些变化的可能决定因素。
符合条件的患者由参与的全科医生挑选。纳入至少有两次血压测量值的高血压患者。进行两级混合效应多元二元逻辑回归分析,以评估所发现效应的可能决定因素。
总体而言,776名患者(平均年龄79.2岁;标准差为8.1岁;年龄范围38 - 98岁)纳入分析。在项目期间,收缩压(从136.1降至131.0 mmHg,P<0.0001)和舒张压(从77.0降至75.7 mmHg,P = 0.0026)的平均值下降。26.0%的患者血压从高血压值变为正常血压值,反之,14.3%的患者血压从正常血压值变为高血压值(P<0.0001)。多级回归模型未显示复杂干预的单个因素是血压转变为正常血压值的决定因素。
尽管该研究是在现实生活条件下进行的,因此存在一些方法学上的局限性,但将家访工作委托给合格的执业助理可能对老年高血压患者血压的变化产生了积极影响。该研究人群代表了一个相关的医疗护理人群,可能会从AGnES概念的实施中受益。