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多器官功能衰竭——血浆置换能发挥作用吗?

Multiple organ failure--a role for plasma exchange?

作者信息

McClelland P, Williams P S, Yaqoob M, Mostafa S M, Bone J M

机构信息

Department of Renal Medicine, Royal Liverpool Hospital, UK.

出版信息

Intensive Care Med. 1990;16(2):100-3. doi: 10.1007/BF02575302.

DOI:10.1007/BF02575302
PMID:2332535
Abstract

Two patients with multiple organ failure, septicaemia and a deteriorating clinical course were treated by plasma exchange in addition to standard supportive measures. Dramatic improvements were seen in cardio-respiratory (patient 1), neurological and renal parameters (patient 2) which were attributable to the exchanges. Plasma exchange might be of value as adjunctive therapy where overwhelming septicaemia occurs with multiple organ failure.

摘要

两名患有多器官功能衰竭、败血症且临床病程不断恶化的患者,除了接受标准的支持性治疗措施外,还接受了血浆置换治疗。在心肺功能方面(患者1)、神经和肾脏参数方面(患者2)均出现了显著改善,这些改善归因于血浆置换。在发生严重败血症并伴有多器官功能衰竭的情况下,血浆置换作为辅助治疗可能具有价值。

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Sepsis and septic shock. II. Treatment.

本文引用的文献

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Pulmonary injury and prostaglandin production during endotoxemia in conscious sheep.清醒绵羊内毒素血症期间的肺损伤与前列腺素生成
Am J Physiol. 1981 Mar;240(3):H348-53. doi: 10.1152/ajpheart.1981.240.3.H348.
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Determinants of organ malfunction or death in patients with intra-abdominal sepsis. A discriminant analysis.腹腔内脓毒症患者器官功能障碍或死亡的决定因素。一项判别分析。
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脓毒症与脓毒性休克。二、治疗
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Meningococcal septicaemia treated with combined plasmapheresis and leucapheresis or with blood exchange.采用血浆置换与白细胞去除术联合或血液置换治疗的脑膜炎球菌败血症。
Br Med J (Clin Res Ed). 1984 Feb 11;288(6415):439-41. doi: 10.1136/bmj.288.6415.439.
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Modification of pulmonary responses to endotoxemia in awake sheep by steroidal and nonsteroidal anti-inflammatory agents.甾体类和非甾体类抗炎药对清醒绵羊内毒素血症肺反应的影响
Am Rev Respir Dis. 1984 Dec;130(6):1140-6. doi: 10.1164/arrd.1984.130.6.1140.
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Infusion of branched-chain enriched amino acid solution in patients with hepatic encephalopathy.向肝性脑病患者输注富含支链氨基酸的溶液。
Ann Surg. 1982 Aug;196(2):209-20. doi: 10.1097/00000658-198208000-00015.
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The effect of plasma exchange on lymphocyte suppression after burn.
Arch Surg. 1984 Jan;119(1):33-8. doi: 10.1001/archsurg.1984.01390130023004.
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Influence of reticuloendothelial functional alterations on mortality patterns in endotoxin and tourniquet shock.
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