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利用D-二聚体诊断无痛性急性主动脉夹层:一例报告

Using d-dimer to diagnose painless acute aortic dissection: a case report.

作者信息

Barniol Caroline, Vallé Baptiste, Dehours Emilie, Charpentier Sandrine, Bounes Vincent, Lauque Dominique

机构信息

Pôle de Médecine d'Urgence, Hôpitaux Universitaires de Toulouse, CHU Purpan, TSA 40031, 31059 Toulouse Cedex 9, France.

出版信息

Case Rep Emerg Med. 2011;2011:395613. doi: 10.1155/2011/395613. Epub 2011 Sep 18.

Abstract

Introduction. Aortic dissection is a cardiovascular emergency; the most frequent symptom is chest pain, but clinical presentation can be varied and atypical. Case Presentation. We report the case of a 66-year-old Caucasian male who presented a syncope immediately followed by a left-arm weakness while driving his car. Clinical examination was normal, but bilateral jugular vein distension was noted. Electrocardiogram and chest radiography were unremarkable. Among blood tests performed, troponin I test result was negative, and D-dimer test concentration was >4000 ng/mL. Since D-dimer test result was positive, chest computer tomography angiogram was performed and found a thoracic aortic dissection. Conclusion. Our case report shows that acute aortic dissection diagnosis is difficult and must be associated with the interpretation of various clinical signs and D-dimer measurement. It could be helpful for the emergency physician to have a pretest probability D-dimer like in pulmonary embolism diagnosis.

摘要

引言。主动脉夹层是一种心血管急症;最常见的症状是胸痛,但临床表现可能多种多样且不典型。病例报告。我们报告一例66岁白种男性病例,该患者在驾车时突发晕厥,随后出现左臂无力。临床检查正常,但发现双侧颈静脉扩张。心电图和胸部X线检查无异常。在进行的血液检查中,肌钙蛋白I检测结果为阴性,D-二聚体检测浓度>4000 ng/mL。由于D-二聚体检测结果为阳性,遂进行胸部计算机断层血管造影,发现胸主动脉夹层。结论。我们的病例报告表明,急性主动脉夹层的诊断困难,必须结合各种临床体征的解读和D-二聚体检测。在诊断中像肺栓塞那样采用D-二聚体的验前概率可能对急诊医生有所帮助。

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