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葡萄糖酸氯己定与聚维酮碘溶液在足部和踝部细菌去污效果的比较:一项初步研究。

Comparison of the effectiveness in bacterial decontamination between chlorhexidine gluconate and povidone-iodine solution in foot and ankle: a pilot study.

作者信息

Rugpolmuang Likit, Thanabodeethada Roongroj, Riansuwan Kongkhet

机构信息

Department of Orthopaedic Surgery, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.

出版信息

J Med Assoc Thai. 2012 Sep;95 Suppl 9:S95-8.

Abstract

BACKGROUND

The decontamination for foot and ankle surgery should be considered as a special preparation due to higher rate of bacterial contamination. The footwear and humidity is also the issue of interest especially in tropical country. The contamination before surgery should be reduced to avoid the infection. The effectiveness of antiseptics and special condition for the foot and ankle surgery should be elucidated for better medical care.

MATERIAL AND METHOD

The twenty volunteers were included in the present study. In group 1, the foot was scrubbed with 7.5% Povidone-lodine and painted with 10% Povidone-lodine solution. In group II, the foot was scrubbed with Chlorhexidine gluconate scrub and painted with 2% Chlorhexidine gluconate in 70% alcohol. At the beginning and end of the preparation, specimens were taking from all toes, nailfold, interdigital web spaces. These samples were sent for aerobic bacterial cultures. The results were interpreted as positive or negative cultivation and the number of bacterial colonies.

RESULTS

All of the samples from 40 feet were collected; In Group I, positive culture was 5 samples (25%). In Group II, positive culture was 2 samples (10%) (p = 0.2).

CONCLUSION

The Chlorhexidine gluconate and Povidone-lodine are effective in reduction the number of bacterial colonization. The steps of preparation before surgery also play an important role in eliminating the pathogenic bacteria. Both antiseptics were found no significant different in efficacy of pathogenic bacteria reduction.

摘要

背景

由于足部和踝关节手术的细菌污染率较高,其去污处理应被视为一种特殊的准备工作。鞋类和湿度也是一个值得关注的问题,尤其是在热带国家。术前污染应予以减少以避免感染。为了提供更好的医疗护理,应阐明足部和踝关节手术中防腐剂的有效性及特殊条件。

材料与方法

本研究纳入了20名志愿者。在第一组中,足部用7.5%聚维酮碘擦洗,并用10%聚维酮碘溶液涂抹。在第二组中,足部用葡萄糖酸洗必泰擦洗,并在70%酒精中用2%葡萄糖酸洗必泰涂抹。在准备工作开始和结束时,从所有脚趾、甲襞、趾间间隙采集标本。这些样本被送去进行需氧细菌培养。结果根据培养结果为阳性或阴性以及细菌菌落数量来解释。

结果

共采集了来自40只脚的所有样本;在第一组中,阳性培养样本有5个(25%)。在第二组中,阳性培养样本有2个(10%)(p = 0.2)。

结论

葡萄糖酸洗必泰和聚维酮碘在减少细菌定植数量方面是有效的。术前准备步骤在消除病原菌方面也起着重要作用。两种防腐剂在减少病原菌效力方面没有显著差异。

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