Kidwai Saera Suhail, Wahid Lubna, Siddiqi Shaista A, Khan Rashid M, Ghauri Ishaq, Sheikh Ishaque
Jinnah Medical College Hospital, SR-6, Sector 7-A, Korangi Industrial Area, Karachi, 75440, Pakistan.
BMC Res Notes. 2013 Jan 17;6:16. doi: 10.1186/1756-0500-6-16.
Musculoskeletal manifestations of diabetes in the upper limb are well recognized. No data has been available in this regard from Pakistan. Our aim was to find out the frequency of upper limb musculoskeletal abnormalities in diabetic patients.
This was an observational study in which type 2 diabetes patients attending our diabetic clinic were enrolled along with age and gender matched controls. Data was analyzed on SPSS 16.
In total, 210 Type 2 diabetics (male 34.3%, female 65.7%) and 203 controls (male 35%, female 65%) were recruited. The mean age was 50.7± 10.2 years in diabetic group as compared to 49.5±10.6 years in the control group. The frequencies of hand region abnormalities were significantly higher in the diabetic subjects as compared to the controls (20.4%, p-value <0.001). Limited joint mobility (9.5% vs 2.5%), carpal tunnel syndrome (9% vs 2%), trigger finger (3.8% vs 0.5%), and dupuytren's contracture (1% vs 0%) were found more frequent as compared to controls (all p-values <0.05). In the shoulder region of diabetic subjects, adhesive capsulitis and tendonitis was found in 10.9% and 9.5% respectively as compared to 2.5% and 2% in control group [p- value <0.001]. A weak but positive relationship was observed between age and duration of diabetes with these upper limb abnormalities. However, no correlation was found between the frequencies of these abnormalities with control of diabetes.
A higher frequency of upper limb musculoskeletal abnormalities was observed in Type 2 diabetic patients as compared to control group.
糖尿病在上肢的肌肉骨骼表现已得到充分认识。巴基斯坦在这方面尚无相关数据。我们的目的是了解糖尿病患者上肢肌肉骨骼异常的发生率。
这是一项观察性研究,纳入了在我们糖尿病诊所就诊的2型糖尿病患者以及年龄和性别匹配的对照组。数据在SPSS 16上进行分析。
共招募了210名2型糖尿病患者(男性34.3%,女性65.7%)和203名对照组(男性35%,女性65%)。糖尿病组的平均年龄为50.7±10.2岁,对照组为49.5±10.6岁。与对照组相比,糖尿病患者手部区域异常的发生率显著更高(20.4%,p值<0.001)。与对照组相比,有限关节活动度(9.5%对2.5%)、腕管综合征(9%对2%)、扳机指(3.8%对0.5%)和掌腱膜挛缩(1%对0%)更为常见(所有p值<0.05)。在糖尿病患者的肩部区域,粘连性关节囊炎和肌腱炎的发生率分别为10.9%和9.5%,而对照组为2.5%和2%[p值<0.001]。观察到年龄和糖尿病病程与这些上肢异常之间存在微弱但正相关的关系。然而,这些异常的发生率与糖尿病控制之间未发现相关性。
与对照组相比,2型糖尿病患者上肢肌肉骨骼异常的发生率更高。