Song Ming, Chen Wen-Kuan, Zhang Quan, Chen Shu-Wei, Zhuang Shi-Min, Yang An-Kui
Department of Head and Neck Surgery and State Key Laboratory of Oncology in South China, Sun Yat-sen University Cancer Center, Guangzhou, PR China.
J Plast Surg Hand Surg. 2013 Feb;47(1):40-5. doi: 10.3109/2000656X.2012.729510.
Irradiation of the recipient site has been associated with postoperative complications and an increased rate of flap failure in facial reconstruction. The aim of this study was to report the outcomes of our use of four different types of flaps (two free and two pedicled) for the reconstruction of patients with nasopharyngeal carcinoma (NPC) treated with radiotherapy, who subsequently received salvage surgery after the development of recurrence or secondary primary tumours. The records of 12 NPC patients who underwent salvage surgery and reconstruction from 2002-2007 were retrospectively reviewed. There were no intraoperative or significant postoperative complications. All flaps survived. The average cosmetic outcome was 2.7 (1 = poor, 4 = excellent), all patients could tolerate a liquid to normal diet, and nine patients had normal or intelligible speech, while three exhibited slurred speech. These results indicate that the effects of irradiation on the recipient site do not appear to adversely affect successful flap transfer or outcomes.
受区照射与面部重建术后并发症及皮瓣失败率增加有关。本研究的目的是报告我们使用四种不同类型皮瓣（两种游离皮瓣和两种带蒂皮瓣）对接受放疗的鼻咽癌（NPC）患者进行重建的结果，这些患者在复发或继发原发性肿瘤后接受了挽救性手术。回顾性分析了2002年至2007年期间12例行挽救性手术和重建的NPC患者的记录。术中及术后均无严重并发症。所有皮瓣均存活。平均美容效果为2.7分（1分=差，4分=优），所有患者均可耐受流食至正常饮食，9例患者言语正常或清晰，3例患者言语含糊不清。这些结果表明，照射对受区的影响似乎不会对皮瓣成功转移或结果产生不利影响。
