Hashimoto Kohei, Horinouchi Hirohisa, Ohtsuka Takashi, Kohno Mitsutomo, Izumi Yotaro, Hayashi Yuichiro, Nomori Hiroaki
Division of General Thoracic Surgery, Department of Surgery, School of Medicine, Keio University, Tokyo, Japan.
Ann Thorac Cardiovasc Surg. 2013;19(6):485-8. doi: 10.5761/atcs.cr.12.01817. Epub 2013 Jan 16.
We present the case of a 56-year-old woman with an anterior mediastinal tumor who has past history of myasthenia gravis and invasive thymoma. Furthermore, she had superior vena cava syndrome that was caused by a rapidly growing tumor. A biopsy proved diffuse large B-cell lymphoma. After 8 courses of chemotherapy, remission of the lymphoma was achieved. Because a second primary malignancy, including lymphoma, can occur in patients with thymoma, a biopsy is necessary for tumors located in the anterior mediastinum, particularly in patients with a history of treatment for thymoma, to distinguish between recurrence and a second primary malignancy.
我们报告一例56岁女性，患有前纵隔肿瘤，既往有重症肌无力和侵袭性胸腺瘤病史。此外，她因肿瘤快速生长导致上腔静脉综合征。活检证实为弥漫性大B细胞淋巴瘤。经过8个疗程的化疗，淋巴瘤达到缓解。由于胸腺瘤患者可能发生包括淋巴瘤在内的第二原发性恶性肿瘤，对于位于前纵隔的肿瘤，特别是有胸腺瘤治疗史的患者，进行活检以区分复发和第二原发性恶性肿瘤是必要的。
