Yanagi Hiromasa, Imoto Kiyotaka, Suzuki Shin-ichi, Uchida Keiji, Masuda Munetaka, Miyashita Akira
Department of Cardiovascular Surgery, Fujisawa City Hospital, Fujisawa, Kanagawa, Japan.
Ann Thorac Cardiovasc Surg. 2013;19(6):456-60. doi: 10.5761/atcs.oa.12.02014. Epub 2013 Jan 16.
Sleep apnea syndrome (SAS) is an independent risk factor for hypertension which is a major risk factor for acute aortic dissection. The purposes of this study were to assess the prevalence of SAS in patients with acute aortic dissection, delineate the characteristics of patients who have acute aortic dissection with SAS.
Of 95 consecutive patients with acute aortic dissection, 13 had episodes of sleep apnea and nocturnal hypoxemia. A portable sleep monitoring system was used to assess sleep status in the 13 patients.
The SAS-positive group consisted of 12 patients (12.6%), 8 with type A dissection and 4 with type B dissection. Age was significantly lower in the SAS-positive group (47.2 ± 8.5 years) than in the SAS-negative group (64.9 ± 10.3 years)(p <0.001). The male:female ratio was significantly higher in the SAS-positive group than in the SAS-negative group (p <0.001). The body mass index was significantly greater in the SAS-positive group than in the SAS-negative group (p <0.001). All 12 patients in the SAS-positive group had hypertension.
Patients who have acute aortic dissection with SAS are characterized by being tall, fat, and relatively young men with hypertension. Sleep apnea syndrome may be a risk factor for acute aortic dissection in middle-aged men.
睡眠呼吸暂停综合征（SAS）是高血压的一个独立危险因素，而高血压是急性主动脉夹层的主要危险因素。本研究的目的是评估急性主动脉夹层患者中SAS的患病率，描述合并SAS的急性主动脉夹层患者的特征。
在95例连续的急性主动脉夹层患者中，13例有睡眠呼吸暂停和夜间低氧血症发作。使用便携式睡眠监测系统评估这13例患者的睡眠状态。
SAS阳性组由12例患者组成（12.6%），其中8例为A型夹层，4例为B型夹层。SAS阳性组的年龄（47.2±8.5岁）显著低于SAS阴性组（64.9±10.3岁）（p<0.001）。SAS阳性组的男女比例显著高于SAS阴性组（p<0.001）。SAS阳性组的体重指数显著高于SAS阴性组（p<0.001）。SAS阳性组的12例患者均患有高血压。
合并SAS的急性主动脉夹层患者的特征是身材高大、肥胖且相对年轻的男性，伴有高血压。睡眠呼吸暂停综合征可能是中年男性急性主动脉夹层的一个危险因素。
