Miller Stacey M, Bellinger Christina R, Chatterjee Arjun
Wake Forest Baptist Health, Winston-Salem, NC 27157, USA.
J Bronchology Interv Pulmonol. 2013 Jan;20(1):38-40. doi: 10.1097/LBR.0b013e318282d3ca.
Benign endobronchial tumors are a rare entity capable of causing significant symptoms. Endobronchial tumor destruction has the potential for relieving symptoms while sparing the patient from invasive surgical resection. Although Nd:YAG laser has been successfully used, other less costly approaches such as argon plasma coagulation (APC) and electrocautery, may be effective alternatives for the bronchoscopic treatment of benign endobronchial tumors.
A retrospective medical chart review was conducted at a single academic center in the United States from the period of January 2005 through December 2011 to collect a minimum of 10 cases for review. Eligibility criteria included diagnosis of a benign endobronchial tumor and age over 18 years. Our institution's pathology database was searched by specific benign tumor and the results were further refined based on an endobronchial location. The bronchoscopic procedure log was also searched and identified procedures were cross referenced with the medical record to confirm eligibility.
Ten patients with pathologically confirmed benign endobronchial tumors were identified. All patients achieved tumor regression with APC in combination with electrocautery or cryotherapy. Majority of the procedures (75%) were performed with flexible bronchoscopy and 55% were performed under moderate sedation.
APC is an effective method for tumor devitalization and reduction in tumor size, making it a viable and less costly therapeutic option for the treatment of benign endobronchial tumors.
良性支气管内肿瘤是一种罕见的疾病,可引起严重症状。支气管内肿瘤破坏有可能缓解症状,同时使患者免于侵入性手术切除。尽管钕钇铝石榴石激光已成功应用,但其他成本较低的方法,如氩等离子体凝固(APC)和电灼术,可能是支气管镜治疗良性支气管内肿瘤的有效替代方法。
在美国的一个学术中心进行了一项回顾性病历审查,时间从2005年1月至2011年12月,收集至少10例病例进行审查。入选标准包括诊断为良性支气管内肿瘤且年龄超过18岁。通过特定的良性肿瘤在我们机构的病理数据库中进行搜索,并根据支气管内位置进一步筛选结果。还搜索了支气管镜操作记录,并将识别出的操作与病历进行交叉核对以确认入选资格。
确定了10例经病理证实的良性支气管内肿瘤患者。所有患者通过APC联合电灼术或冷冻疗法实现了肿瘤消退。大多数操作(75%)通过柔性支气管镜进行,55%在中度镇静下进行。
APC是一种使肿瘤失活并缩小肿瘤大小的有效方法,使其成为治疗良性支气管内肿瘤的一种可行且成本较低的治疗选择。