Frykberg Robert G, Gordon Scott, Tierney Edward, Tallis Arthur
Department of Podiatry, Carl T. Hayden VA Medical Center, Phoenix, AZ 85012, USA.
J Am Podiatr Med Assoc. 2013 Jan-Feb;103(1):67-72. doi: 10.7547/1030067.
Heparin is an anticoagulant commonly used to treat and prevent deep venous thrombosis. Heparin-induced thrombocytopenia and possible thrombosis are serious complications associated with its use. This can occasionally complicate treatment of patients undergoing podiatric surgery. Heparin-induced thrombocytopenia is often not immediately recognized and is underreported in podiatric medicine literature. The goal of this case report is to highlight the multiple risk factors associated with the development of heparin-induced thrombocytopenia and to aid with early recognition, understanding of pathogenesis, and treatment options.
肝素是一种常用于治疗和预防深静脉血栓形成的抗凝剂。肝素诱导的血小板减少症及可能出现的血栓形成是与其使用相关的严重并发症。这偶尔会使接受足科手术的患者的治疗复杂化。肝素诱导的血小板减少症往往不能立即被识别,且在足科医学文献中报告不足。本病例报告的目的是强调与肝素诱导的血小板减少症发生相关的多种风险因素,并有助于早期识别、理解发病机制及治疗选择。