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患有肺动脉高压的早产儿的医疗保健利用和呼吸发病率。

Health-care utilization and respiratory morbidities in preterm infants with pulmonary hypertension.

机构信息

Eudowood Division of Pediatric Respiratory Sciences, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA.

出版信息

J Perinatol. 2013 Jul;33(7):543-7. doi: 10.1038/jp.2012.170. Epub 2013 Jan 17.

Abstract

OBJECTIVE

To assess health-care utilization and risk of respiratory morbidities in preterm infants with bronchopulmonary dysplasia (BPD) and pulmonary hypertension (PH).

STUDY DESIGN

Retrospective data were obtained from subjects (n=109) attending a BPD clinic. Subjects were stratified by the presence or absence of PH before and after 2 months of age. Analytic methods included t-tests, χ(2) tests and regression.

RESULT

Subjects with BPD and PH present after 2 months of age were hospitalized for 2.2 months longer than those without PH (P=0.02). These subjects were 4.5 times more likely to receive home supplemental oxygen or mechanical ventilation (P=0.03). No difference in the risk of respiratory morbidities after initial hospital discharge was seen with PH.

CONCLUSION

PH in preterm infants is associated with longer initial hospitalizations and a higher likelihood of requiring home respiratory support. This has implications for counseling families and reducing the medical, psychosocial, and economic burden of BPD and PH.

摘要

目的

评估患有支气管肺发育不良(BPD)和肺动脉高压(PH)的早产儿的医疗保健利用情况和呼吸系统疾病风险。

研究设计

本研究回顾性地收集了参加 BPD 门诊的患者(n=109)的数据。根据患者在 2 月龄前和后是否存在 PH 进行分层。分析方法包括 t 检验、卡方检验和回归分析。

结果

在 2 月龄后出现 PH 的 BPD 患者的住院时间比无 PH 的患者长 2.2 个月(P=0.02)。这些患者接受家庭补充氧气或机械通气的可能性是无 PH 患者的 4.5 倍(P=0.03)。在初次出院后,PH 与呼吸系统疾病风险无差异。

结论

早产儿 PH 与较长的初始住院时间和更有可能需要家庭呼吸支持相关。这对咨询家庭和减轻 BPD 和 PH 的医疗、心理社会和经济负担具有重要意义。

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