Mohammadi Mohammad Reza, Zhand Pouya, Mortazavi Moghadam Behnoush, Golalipour Mohammad Jafar
Department of Neurosurgery, 5 Azar Hospital, Golestan University of Medical Sciences, Gorgan, Iran.
Iran J Radiol. 2011 Dec;8(4):218-23. doi: 10.5812/iranjradiol.4495. Epub 2011 Dec 25.
Morphometric measurements of the corpus callosum (CC) are important to have normative values according to sex, age and race/ethnicity.
This study was done to measure the size of CC and to identify its gender- and age-related differences in the North of Iran.
The size of CC on midsagittal section was measured in 100 (45 males, 55 females) normal subjects using magnetic resonance imaging (MRI) admitted to the Kowsar MRI center in Gorgan-Northern Iran. Longitudinal and vertical dimensions of the CC, longitudinal and vertical lengths of the brain and the length of genu and splenium were measured. Data were analyzed by student's unpaired t test, ANOVA and regression analysis.
The anteroposterior length and vertical dimension of the CC, the length of genu and splenium were larger in males than in females, but these differences were not significant. The anteroposterior and vertical lengths of the brain were significantly larger in males than in females (P < 0.05). The length of CC increased with age and regression equations for predicting age were derived from the length of the CC. There was also a positive significant correlation between the anteroposterior length of the CC and the length of the brain and vertical dimension of the CC.
This study showed that various CC parameters vary with the values documented in the Caucasian, Indian and Japanese population.
胼胝体（CC）的形态测量对于获取基于性别、年龄和种族/民族的正常参考值很重要。
本研究旨在测量伊朗北部人群的CC大小，并确定其与性别和年龄相关的差异。
在伊朗北部戈尔甘的科萨尔MRI中心，对100名正常受试者（45名男性，55名女性）进行磁共振成像（MRI）检查，测量矢状面中段CC的大小。测量CC的纵向和垂直尺寸、大脑的纵向和垂直长度以及膝部和压部的长度。数据采用学生独立样本t检验、方差分析和回归分析。
男性CC的前后长度和垂直尺寸、膝部和压部的长度均大于女性，但差异不显著。男性大脑的前后长度和垂直长度显著大于女性（P < 0.05）。CC的长度随年龄增长，根据CC的长度得出了预测年龄的回归方程。CC的前后长度与大脑长度和CC的垂直尺寸之间也存在显著正相关。
本研究表明，CC的各种参数与白种人、印度人和日本人人群中记录的值有所不同。
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