Kurenkov A L, Batysheva T T, Vinogradov A V, Ziuziaeva E K
Zh Nevrol Psikhiatr Im S S Korsakova. 2012;112(7 Pt 2):24-8.
Spasticity in children cerebral palsy has its own peculiarities due to the presence of pathological tonic reflexes, pathological sinkinetic activity during arbitrary movements, disturbance of coordinative interactions of muscle synergists and antagonists, increase of total reflex excitability. Physiotherapeutic methods, massage, therapeutic exercises, kinesitherapy, biological feedback training (BFT), methods of orthopedic correction, neurosurgery are widely used in the treatment of spasticity. The use of botulinum toxin type A is a new effective approach to the treatment of spasticity that improves motor functions and quality of life of children with children cerebral palsy. It is being used in the treatment of children and adolescence in a polyclinic unit of the Moscow psychoneurological hospital since 2001. The experience of treatment with botulinum and wide implementation of this method indicated that botulinum toxin injections in the complex treatment of spasticity allow to optimize approaches to treatment of children and adolescence with children cerebral palsy and to increase significantly the quality of medical-social rehabilitation of patients.
由于存在病理性紧张性反射、随意运动时的病理性运动徐缓活动、肌肉协同肌和拮抗肌协调相互作用紊乱以及总反射兴奋性增加，小儿脑瘫中的痉挛有其自身特点。物理治疗方法、按摩、治疗性运动、运动疗法、生物反馈训练（BFT）、矫形矫正方法、神经外科手术在痉挛治疗中被广泛应用。使用A型肉毒杆菌毒素是治疗痉挛的一种新的有效方法，可改善小儿脑瘫患儿的运动功能和生活质量。自2001年以来，莫斯科精神神经医院的门诊科室一直在将其用于儿童和青少年的治疗。肉毒杆菌治疗经验及该方法的广泛应用表明，在痉挛的综合治疗中注射肉毒杆菌毒素可优化小儿脑瘫儿童和青少年的治疗方法，并显著提高患者的医疗-社会康复质量。
