Chutko L S, Surushkina S Iu, Bykova Iu L, Iakovenko E A, Aĭtbekov K A, Nikishena I S, Anisimova T I
Zh Nevrol Psikhiatr Im S S Korsakova. 2012;112(7 Pt 2):84-9.
We examined 162 patients, aged from 10 to 15 years, with tic hyperkineses. Transient and chronic tic disorders were observed in 82 and 80 patients, respectively. The relationship of clinical features, frequency, psychological and encephalographic characteristics of the patients with age-at-onset was studied. The effect of adaptol on the course of chronic tic disorders was evaluated. In addition to our results reported previously for transient tic disorders, we demonstrated the efficacy of adaptol administered in dose 1000 mg per day during 60 days in patients with chronic tic disorders.
我们对162例年龄在10至15岁之间患有抽动多动障碍的患者进行了检查。分别在82例和80例患者中观察到短暂性和慢性抽动障碍。研究了患者的临床特征、发作频率、心理和脑电图特征与发病年龄之间的关系。评估了阿得诺对慢性抽动障碍病程的影响。除了我们之前报道的关于短暂性抽动障碍的结果外,我们还证明了在慢性抽动障碍患者中,每天服用1000毫克阿得诺,持续60天的疗效。