Department of Otolaryngology, University of Pittsburgh Medical Center, PA, USA.
Oral Oncol. 2013 May;49(5):401-6. doi: 10.1016/j.oraloncology.2012.12.009. Epub 2013 Jan 16.
Stereotactic Body Radiotherapy (SBRT) is increasingly used to treat a variety of head and neck tumors as a result of its highly conformal dose distributions and stereotactic spatial accuracy in delivery. Our experience and other previous reports have shown that SBRT is technically feasible, well-tolerated and compares favorably to other alternatives of salvage therapy in the management of patients with recurrent and/or previously irradiated head and neck cancers. Furthermore, it has the advantage of a shorter treatment schedule, greater compliance, and safe delivery in the outpatient setting. This affords an opportunity to introduce SBRT as a definitive treatment in select patients. This review presents an overview of the use of SBRT for managing head and neck tumors by highlighting the existing indications and the expanding role of SBRT in managing these patients.
立体定向体部放射治疗(SBRT)因其高度适形的剂量分布和精确的立体空间定位,在治疗各种头颈部肿瘤方面的应用日益增多。我们的经验和其他先前的报告表明,SBRT 在技术上是可行的,患者耐受性良好,并且在治疗复发性和/或先前接受过放疗的头颈部癌症患者的挽救性治疗方面,与其他替代方法相比具有优势。此外,它还具有治疗方案更短、患者顺应性更高、以及在门诊环境下安全治疗的优势。这为将 SBRT 作为某些特定患者的确定性治疗方法提供了机会。本综述通过强调 SBRT 治疗头颈部肿瘤的现有适应证和 SBRT 在治疗这些患者中的扩展作用,对头颈部肿瘤的 SBRT 治疗进行了概述。