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原发性乳腺癌的立体定向部分乳腺照射：现状与未来方向的全面综述

Stereotactic partial breast irradiation in primary breast cancer: A comprehensive review of the current status and future directions.

作者信息

Takanen Silvia, Pinnarò Paola, Farina Ilaria, Sperati Francesca, Botti Claudio, Vici Patrizia, Soriani Antonella, Marucci Laura, Sanguineti Giuseppe

机构信息

Radiation Oncology, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Regina Elena National Cancer Institute, Rome, Italy.

Biostatistics, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Regina Elena National Cancer Institute, Rome, Italy.

出版信息

Front Oncol. 2022 Oct 13;12:953810. doi: 10.3389/fonc.2022.953810. eCollection 2022.

DOI:10.3389/fonc.2022.953810
PMID:36313648
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9606691/
Abstract

UNLABELLED

In selected low-risk breast cancer patients, accelerated partial breast irradiation (APBI) may represent an alternative option to the whole breast irradiation to reduce the volume of irradiated breast and total treatment duration. In the last few years, preliminary data from clinical trials showed that stereotactic partial breast radiotherapy may have the advantage to be less invasive compared to other APBI techniques, with preliminary good results in terms of local toxicity and cosmesis: the use of magnetic resonance, fiducial markers in the tumor bed, and new breast devices support both a precise definition of the target and radiation planning.

SYSTEMATIC REVIEW REGISTRATION

https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42021257856, identifier CRD42021257856.

摘要

未标注

在部分低风险乳腺癌患者中，加速部分乳腺照射（APBI）可能是全乳照射的替代选择，以减少受照射乳腺的体积和总治疗时间。在过去几年中，临床试验的初步数据表明，与其他APBI技术相比，立体定向部分乳腺放疗可能具有侵入性较小的优势，在局部毒性和美容效果方面初步取得了良好结果：使用磁共振、瘤床中的基准标记物以及新型乳腺设备有助于精确界定靶区和进行放射治疗计划。

系统评价注册

https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42021257856，标识符CRD42021257856。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb02/9606691/bb97bb16cd5e/fonc-12-953810-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb02/9606691/bea33f4d78ec/fonc-12-953810-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb02/9606691/bb97bb16cd5e/fonc-12-953810-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb02/9606691/bea33f4d78ec/fonc-12-953810-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb02/9606691/bb97bb16cd5e/fonc-12-953810-g002.jpg

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本文引用的文献

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Int J Radiat Oncol Biol Phys. 2022 Mar 1;112(3):663-670. doi: 10.1016/j.ijrobp.2021.10.010. Epub 2021 Oct 25.
2
MRI Response to Pre-operative Stereotactic Ablative Body Radiotherapy (SABR) in Early Stage ER/PR+ HER2- Breast Cancer correlates with Surgical Pathology Tumor Bed Cellularity.早期 ER/PR+HER2- 乳腺癌术前立体定向消融体放射治疗（SABR）的 MRI 反应与手术病理肿瘤床细胞密度相关。
Clin Breast Cancer. 2022 Feb;22(2):e214-e223. doi: 10.1016/j.clbc.2021.06.016. Epub 2021 Jul 20.
3
5-year results of accelerated partial breast irradiation (APBI) with SBRT (stereotactic body radiation therapy) and exactrac adaptive gating (Novalis) for very early breast cancer patients: was it all worth it?早期乳腺癌患者立体定向体部放射治疗（SBRT）加 Novalis 精确放疗自适应门控技术（exactrac）加速部分乳腺照射（APBI）的 5 年结果：一切是否值得？
Clin Transl Oncol. 2021 Nov;23(11):2358-2367. doi: 10.1007/s12094-021-02636-3. Epub 2021 May 27.
4
Intraoperative irradiation for early breast cancer (ELIOT): long-term recurrence and survival outcomes from a single-centre, randomised, phase 3 equivalence trial.早期乳腺癌术中放疗（ELIOT）：来自单中心、随机、3 期等效性试验的长期复发和生存结果。
Lancet Oncol. 2021 May;22(5):597-608. doi: 10.1016/S1470-2045(21)00080-2. Epub 2021 Apr 9.
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