Sokolić-Mihalak Darja, Frece Jadranka, Slavica Anita, Delaš Frane, Pavlović Hrvoje, Markov Ksenija
Croatian Food Agency, Osijek, Croatia.
Arh Hig Rada Toksikol. 2012 Dec;63(4):457-62. doi: 10.2478/10004-1254-63-2012-2309.
The aim of this study was to determine the effects of the essential oil of Thymus serpyllum L. and of its components thymol and total phenols (total phenolic content, TPC) extracted from the plant on the growth and mycotoxin production of Aspergillus ochraceus, A. carbonarius, and A. niger. Minimal inhibitory concentration (MIC) determined for the essential oil and thymol, and selected concentration of the TPC extract inhibited fungal growth and ochratoxin A biosynthesis by more than 60 %, depending on the conditions and duration of incubation with the fungi. Essential oil showed the strongest inhibitory effect which may have been related to the synergistic or cumulative effects of its components.
本研究的目的是确定百里香精油及其从该植物中提取的成分百里香酚和总酚(总酚含量,TPC)对赭曲霉、黑曲霉和炭黑曲霉生长及霉菌毒素产生的影响。所测定的精油和百里香酚的最低抑菌浓度(MIC)以及TPC提取物的选定浓度,根据与真菌培养的条件和持续时间,可抑制真菌生长和赭曲霉毒素A生物合成达60%以上。精油显示出最强的抑制作用,这可能与其成分的协同或累积效应有关。