Department of Haematology, Skåne University hospital, Lund, Sweden.
Bone Marrow Transplant. 2013 Aug;48(8):1133-7. doi: 10.1038/bmt.2012.283. Epub 2013 Jan 21.
The first international recommendations and guidelines for the care of sibling stem cell donors were established in 2010, and have not yet been evaluated. However, a model for information and care of adult potential sibling stem cell donors (the IC model) developed and introduced at the Skåne University Hospital, Lund, Sweden, in 2005 conforms closely to them. The IC model aims to protect the privacy of potential donors, support and respect their free choice, and identify quickly those unwilling or unable to donate and thus minimize delay in seeking alternative donors. To evaluate the IC model a questionnaire survey in 2010 gathered the perceptions and views on information provision; influences over decision making; and care provision under the IC model of 148 adult siblings informed about SCT donation, and asked to undergo HLA-typing since September 2005 at the hospital. The results suggest the IC model works well but highlights areas for improvement, such as in delivery of HLA typing results to non-matched siblings, and a need to further prevent complicating influence from health professionals and relatives on the decision to undergo HLA typing. Thus improved, the IC model could provide the groundwork for other SCT units seeking to implement the recommendations and guidelines.
2010 年首次制定了有关同胞干细胞供者照护的国际建议和指南，但尚未进行评估。然而，2005 年在瑞典隆德的斯科讷大学医院开发并引入了一种针对成人潜在同胞干细胞供者的信息和照护模式（IC 模式），该模式与建议和指南非常吻合。IC 模式旨在保护潜在供者的隐私，支持并尊重他们的自由选择，并快速识别那些不愿意或不能捐赠的人，从而最大程度地减少寻找替代供者的延迟。为了评估 IC 模式，2010 年进行了一项问卷调查，调查了 148 名成年同胞对信息提供、决策影响以及自 2005 年 9 月以来在该医院接受 SCT 捐赠并要求进行 HLA 分型的知情同意的看法和意见。结果表明，IC 模式运作良好，但也凸显了一些需要改进的领域，例如向非匹配同胞提供 HLA 分型结果，以及需要进一步防止卫生专业人员和亲属对进行 HLA 分型的决策产生复杂影响。经过改进，IC 模式可以为其他寻求实施建议和指南的 SCT 单位提供基础。
