副赫喹胺对沙土鼠（长爪沙鼠）体内未成熟结肠毛圆线虫的疗效。
Efficacy of paraherquamide against immature Trichostrongylus colubriformis in the gerbil (Meriones unguiculatus).
作者信息
Ostlind D A, Mickle W G, Ewanciw D V, Andriuli F J, Campbell W C, Hernandez S, Mochales S, Munguira E
机构信息
Merck Institute for Therapeutic Research, Rahway, New Jersey.
出版信息
Res Vet Sci. 1990 Mar;48(2):260-1.
PMID:2333436
Abstract
Paraherquamide was 98 to 100 per cent effective against six-day-old Trichostrongylus colubriformis infections in gerbils when given as single oral doses of 1.56 mg kg-1 and above. Doses of 0.78 or 0.39 mg kg-1 were 96 and 66 per cent effective, respectively. A single oral dose of 200 mg kg-1 was well tolerated.
摘要
当以1.56毫克/千克及以上的单次口服剂量给药时，副赫曲霉素对沙土鼠体内6日龄的结肠毛圆线虫感染的有效率为98%至100%。0.78毫克/千克或0.39毫克/千克的剂量有效率分别为96%和66%。200毫克/千克的单次口服剂量耐受性良好。
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