Bakkour Waseem, Motta Luisa, Stewart Elizabeth
Department of Dermatology, Salford Royal NHS Foundation Trust, Stott lane, Salford, United Kingdom.
Am J Dermatopathol. 2013 Jun;35(4):489-90. doi: 10.1097/DAD.0b013e31827eaee9.
Erythromelalgia clinically presents with episodic burning, erythema, and warmth of acral sites. It can be divided into primary and secondary associated with myeloproliferative and autoimmune conditions. Histology commonly shows capillary proliferation, swelling of endothelial cells, perivascular edema, and chronic inflammation with sparse lymphocytic infiltrate. We report a case of a 55-year-old man with classical secondary erythromelalgia clinically; however, he had unusual histological findings on biopsy comprising of acute perivascular infiltrate and perivascular mucin. This is the first report of such findings in the context of secondary erythromelalgia.
红斑性肢痛症临床上表现为肢端部位发作性灼痛、红斑和发热。它可分为与骨髓增殖性疾病和自身免疫性疾病相关的原发性和继发性。组织学检查通常显示毛细血管增生、内皮细胞肿胀、血管周围水肿以及伴有稀疏淋巴细胞浸润的慢性炎症。我们报告一例55岁男性患者，临床上患有典型的继发性红斑性肢痛症；然而，他活检时的组织学表现不寻常，包括急性血管周围浸润和血管周围黏蛋白。这是继发性红斑性肢痛症背景下此类发现的首例报告。
