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真性红细胞增多症中的足烧灼感——伴红斑性肢痛症的周围感觉运动性轴索性神经病

Burning feet in polycythemia vera - peripheral sensorimotor axonal neuropathy with erythromelalgia.

作者信息

Wollina Uwe

机构信息

Department of Dermatology and Allergology, Academic Teaching Hospital Dresden-Friedrichstadt, Dresden, Germany.

出版信息

Int J Gen Med. 2015 Feb 2;8:69-71. doi: 10.2147/IJGM.S78848. eCollection 2015.

DOI:10.2147/IJGM.S78848
PMID:25674012
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4321571/
Abstract

Polycythemia vera is a rare myeloproliferative disease. Cutaneous symptoms are uncommon. We report about a 72-year-old female patient with JAK2(V617F) -positive polycythemia who developed peripheral sensorimotor axonal neuropathy and erythromelalgia. Possible causes and treatment are discussed.

摘要

真性红细胞增多症是一种罕见的骨髓增殖性疾病。皮肤症状并不常见。我们报告了一名72岁的女性患者，患有JAK2（V617F）阳性真性红细胞增多症，并发周围感觉运动性轴索性神经病和红斑性肢痛症。文中讨论了可能的病因及治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f121/4321571/1a86cfca2652/ijgm-8-069Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f121/4321571/1a86cfca2652/ijgm-8-069Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f121/4321571/1a86cfca2652/ijgm-8-069Fig1.jpg

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本文引用的文献

1
How common are myeloproliferative neoplasms? A systematic review and meta-analysis.骨髓增殖性肿瘤的发病率有多高？一项系统评价和荟萃分析。
Am J Hematol. 2014 Jun;89(6):581-7. doi: 10.1002/ajh.23690.
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WHO-histological criteria for myeloproliferative neoplasms: reproducibility, diagnostic accuracy and correlation with gene mutations and clinical outcomes.世界卫生组织（WHO）髓系增殖性肿瘤的组织学标准：可重复性、诊断准确性及其与基因突变和临床结果的相关性。
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Janus kinase inhibitors for the treatment of myeloproliferative neoplasms.
系统性疾病的神经肌肉问题。
Curr Neurol Neurosci Rep. 2015 Jul;15(7):48. doi: 10.1007/s11910-015-0565-x.
用于治疗骨髓增殖性肿瘤的 Janus 激酶抑制剂
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4
Determination of accuracy of polycythemia vera diagnoses and use of the JAK2V617F test in the diagnostic scheme.真性红细胞增多症诊断准确性的确定和 JAK2V617F 检测在诊断方案中的应用。
Ann Hematol. 2014 Sep;93(9):1467-72. doi: 10.1007/s00277-014-2068-2. Epub 2014 Apr 1.
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Hydroxyurea-associated acral erythema in a patient with polycythemia vera.
Am J Hematol. 2014 Sep;89(9):931-2. doi: 10.1002/ajh.23698. Epub 2014 Apr 15.
6
Current applications of therapeutic phlebotomy.治疗性放血术的当前应用。
Blood Transfus. 2014 Jan;12 Suppl 1(Suppl 1):s75-83. doi: 10.2450/2013.0299-12. Epub 2013 Oct 3.
7
Sensomotor axonal peripheral neuropathy as a first complication of polycythemia rubra vera: A report of 3 cases.感觉运动性轴索性周围神经病作为真性红细胞增多症的首发并发症：3例报告
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