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泰国注射吸毒者中丙型肝炎检测率低:对基于同伴的干预措施的影响。

Low rates of hepatitis C testing among people who inject drugs in Thailand: implications for peer-based interventions.

机构信息

British Columbia Centre for Excellence in HIV/AIDS, St. Paul's Hospital, 608-1081 Burrard Street, Vancouver, BC, Canada V6Z 1Y6.

出版信息

J Public Health (Oxf). 2013 Dec;35(4):578-84. doi: 10.1093/pubmed/fds105. Epub 2013 Jan 18.

DOI:10.1093/pubmed/fds105
PMID:23335599
Abstract

BACKGROUND

Regular testing for hepatitis C virus (HCV) provides an opportunity for HCV prevention and treatment efforts. In Thailand, the barriers and facilitators of HCV testing among people who inject drugs (IDU) are not known.

METHODS

Using data derived from the Mitsampan Community Research Project between July and October 2011, we assessed the prevalence and factors associated with ever having been tested for HCV antibodies using bivariate statistics and multivariate logistic regression.

RESULTS

Among 427 participants, 141 (33.0%) reported a history of HCV antibody testing. In multivariate analyses, factors positively associated with receiving an HCV antibody test included higher than secondary education [adjusted odds ratio (AOR) = 2.20; 95% confidence interval (CI): 1.35-3.64], binge drug use (AOR = 1.81; 95% CI: 1.12-2.93), methadone treatment enrollment (AOR = 3.47; 95% CI: 1.85-6.95) and having received peer-based education on HCV (AOR = 4.22; 95% CI: 2.66-6.77).

CONCLUSIONS

We found one-third of Thai IDU in our sample reporting a history of HCV testing. The finding that IDU who received peer-based HCV education were more likely to access HCV testing provides evidence for the value of peer-based interventions for this population.

摘要

背景

定期检测丙型肝炎病毒(HCV)为 HCV 的预防和治疗工作提供了机会。在泰国,尚不清楚注射吸毒者(IDU)进行 HCV 检测的障碍和促进因素。

方法

使用 2011 年 7 月至 10 月 Mitsampan 社区研究项目的数据,我们通过双变量统计和多变量逻辑回归评估了 HCV 抗体检测的既往史及其相关因素。

结果

在 427 名参与者中,有 141 名(33.0%)报告了 HCV 抗体检测史。在多变量分析中,与接受 HCV 抗体检测呈正相关的因素包括受过高于中学教育(调整后的优势比(AOR)=2.20;95%置信区间(CI):1.35-3.64)、滥用药(AOR=1.81;95%CI:1.12-2.93)、美沙酮治疗登记(AOR=3.47;95%CI:1.85-6.95)和接受基于同伴的 HCV 教育(AOR=4.22;95%CI:2.66-6.77)。

结论

我们发现,我们样本中三分之一的泰国 IDU 有 HCV 检测史。基于同伴的 HCV 教育使 IDU 更有可能接受 HCV 检测的发现为该人群的同伴干预措施提供了价值证据。

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