Halouzka R, Nechvátal M
Vysoká skola veterinární, Brno.
Vet Med (Praha). 1990 Jan;35(1):49-56.
This paper describes 17 cases of digital spinocellular carcinomas of the limbs of the schnauzer dogs (14 in males and 3 in females) which were diagnosed from July 1987 to the end of 1988. During comparison of the prevalence of these neoplasmas over the period 1975 to 1984, when 11 cases of spinaliomas were diagnosed in dogs, there is an uncommonly high and interesting incidence of these tumors in schnauzers. Spinaliomas were not diagnosed in other breeds and in other locations. We know of no other similar observation. The tumour had the appearance of a poorly mending wound or panaritium and they locally destroyed the digits of the affected individuals. Recurrence was observed once, metastases in lymphatic nodes or other tissues were not observed up to the present time. Histologically the tumors had the appearance of well differentiated spinocellular carcinomas with a fibro-producing and intensive inflammatory reaction. The sarcomatous appearance of the tumor parenchyma was sporadically observed. Lesions were indications for the amputation of the affected digits. As possible etiological factors the authors consider, besides traumatic influences of the overgrown claws, even hormonal and infectious influences.
本文描述了1987年7月至1988年底确诊的17例雪纳瑞犬四肢指(趾)部棘细胞癌(14例雄性,3例雌性)。在比较1975年至1984年期间这些肿瘤的患病率时,当时诊断出11例犬脊髓瘤,雪纳瑞犬中这些肿瘤的发病率异常高且有趣。在其他品种和其他部位未诊断出脊髓瘤。我们未发现其他类似观察结果。肿瘤表现为愈合不良的伤口或脓性指头炎,局部破坏患病个体的指(趾)。观察到1例复发,目前未观察到淋巴结或其他组织转移。组织学上,肿瘤表现为高分化棘细胞癌,伴有纤维生成和强烈炎症反应。偶尔观察到肿瘤实质的肉瘤样外观。病变是患指(趾)截肢的指征。作为可能的病因,作者认为,除了过长爪子的创伤性影响外,甚至还有激素和感染性影响。