Paediatric Intensive Care Unit, Great Ormond Street Hospital for Children, London, UK.
Pediatr Crit Care Med. 2013 Feb;14(2):e85-92. doi: 10.1097/PCC.0b013e3182712997.
A number of studies have reported on parental/clinician reports of children's quality of life after intensive care treatment. The aim of this study was to establish children's own views of their outcome. [corrected].
Prospective cohort study. [corrected].
Twenty-one bed PICU in a tertiary Children's Hospital.
Ninety-seven children aged over 7 yr, with no preexisting learning difficulties, consecutively admitted to PICU over an 18 month period
Patients completed the Pediatric Quality of Life Inventory and a post-traumatic stress screener, at 3 months and again at 1 year (n = 72) after discharge from PICU.
At 3 months post-discharge, the mean total Pediatric Quality of Life Inventory score reported by the PICU group was lower than that reported in the literature for a non-clinical community sample (PICU mean = 79.1 vs community mean = 83.9, p = 0.003), but by 1 year, they were comparable (82.2, p = 0.388). The mean physical functioning subscale score remained lower (PICU mean=81.6 vs. community mean=88.5, p = 0.01), but improved significantly from 73.4 at 3 months (p = 0.001).Sub-group analyses revealed that the elective group reported higher emotional functioning than the community sample (91.0, p=0.005 at 3 months and 88.2, p = 0.038 at 1 year vs community mean=78.5), and made significant gains in social functioning between timepoints (79.1 to 91.4, p = 0.015).Finally, although total PedsQL scores at 1 year were not associated with measures of severity of illness during admission, they were significantly negatively associated with concurrent post-traumatic stress symptom scores (r = -0.40, p = 0.001).
The self-report version of the Pediatric Quality of Life Inventory proved to be a feasible and sensitive tool for assessing health related quality of life in this group of PICU survivors.
许多研究报告了父母/临床医生对重症监护治疗后儿童生活质量的报告。本研究的目的是确定儿童对自己结果的看法。
前瞻性队列研究。
三级儿童医院 21 张病床的 PICU。
97 名年龄超过 7 岁、无先前学习困难的儿童，在 18 个月的时间内连续入住 PICU。
患者在 PICU 出院后 3 个月和 1 年（n = 72）时完成了儿童生活质量量表和创伤后应激筛查器。
出院后 3 个月，PICU 组报告的儿童生活质量量表总分低于文献中报道的非临床社区样本（PICU 平均值= 79.1，社区平均值= 83.9，p = 0.003），但 1 年后，两者相当（82.2，p = 0.388）。身体功能子量表的平均得分仍然较低（PICU 平均值= 81.6，社区平均值= 88.5，p = 0.01），但从 3 个月时的 73.4 显著改善（p = 0.001）。亚组分析表明，选择性组报告的情绪功能高于社区样本（3 个月时为 91.0，p = 0.005，1 年时为 88.2，p = 0.038，社区平均值为 78.5），并且在两个时间点之间在社会功能方面取得了显著进步（79.1 到 91.4，p = 0.015）。最后，尽管 1 年时的 PedsQL 总分与住院期间疾病严重程度的测量值无关，但它们与同期创伤后应激症状评分显著负相关（r = -0.40，p = 0.001）。
儿童生活质量量表的自我报告版本被证明是一种可行且敏感的工具，可用于评估这组 PICU 幸存者的健康相关生活质量。
