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带血管化大转子骨块移植、游离髂骨瓣联合打压植骨治疗股骨头坏死。

Vascularised greater trochanter bone graft, combined free iliac flap and impaction bone grafting for osteonecrosis of the femoral head.

机构信息

Department of Orthopaedics, The First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine, Baiyun District, Zip code 510405, GuangZhou City, Guangdong Province, China.

出版信息

Int Orthop. 2013 Mar;37(3):391-8. doi: 10.1007/s00264-012-1773-5. Epub 2013 Jan 23.

DOI:10.1007/s00264-012-1773-5
PMID:23340673
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3580089/
Abstract

PURPOSE

To investigate the curative efficacy of osteonecrosis of the femoral head (ONFH) in a hip-preserving operative approach, by grafting a vascularized greater trochanter flap combined with a free iliac flap, in an attempt to seek an innovative approach for patients who suffered middle to late stage ONFH without total hip arthroplasty (THA) surgery.

METHOD

Our research included a total of 60 patients (66 hips) who accepted hip-preserving surgery by grafting a vascularized greater trochanter flap combined with a free iliac flap which was tightly filled by hammering because of ONFH (most were Association Research Circulation Osseous (ARCO) stage III patients) from January, 2006 to December, 2010. A Harris Hip Score was obtained during follow-ups, evaluating the clinical efficacy, X-rays were taken regularly for image assessing, and the SF-36 scale was used for estimating quality of life. Terminal observation time was considered when patients had symptom-dependant indications for performing another hip-preserving surgery or THA surgery.

RESULTS

Fifty-eight patients (64 hips) were eventually contacted by telephone for an out-patient clinic return visit, with a mean follow-up time of 35.8 months (varied from 12 months to 60 months), but two patients lost contact for various reasons. The demographic data were as follows: there were 16 ARCO IIIA cases, 22 ARCO IIIB cases, and 26 ARCO IIIC cases, respectively. Postoperative X-rays revealed a well-repaired necrotic area of the femoral head and improvement of femoral-acetabulum coverage. The last follow-up mean Harris Hip Score was 86.56 ± 7.38 (excellent results reached 87.50%), which were greatly improved compared to 50.95 ± 6.86 pre-operatively. Also the postoperative mean scores of all dimensions of the SF-36 scale were improved to some extent. Additionally the physical component summary (PSC) scores were enhanced from 42 ± 13 pre-operatively to 78 ± 11, while the postoperative mental component summary (MCS) scores (76 ± 11) largely increased in contrast to pre-operative scores (51 ± 10), with both target indices having statistical significance (p = 0.005, p = 0.01), signifying hugely improvement of the quality of life of the patients. A correlation was found between Harris Hip Score and all dimensions of SF-36 scale (r = 0.32-0.72), especially closely correlated with physical functioning (PF), role-physical (RP) and bodily pain (BP) in PCS aspect (r = 0.72, p < 0.01; r = 0.58, p < 0.01; r = 0.65, p < 0.01, respectively).

CONCLUSION

There is definite curative efficacy for the treatment of ONFH with an hip-preserving operative approach by grafting a vascularized greater trochanter flap combined with a free iliac flap which was tightly filled by hammering. This kind of operative approach reconstructs the biological stability of femoral head, which promotes repair of necrotic areas and indirectly preserves the femoral head of patients and a majority of hip function. It possesses vast clinical as well as practical significance, because the long-term efficacy can satisfy fundamental life requirements, especially for those young and middle-aged patients who suffer ONFH to avoid or put off the time of total hip arthroplasty (THA) surgery.

摘要

目的

探讨带血管蒂大转子骨瓣复合游离髂骨瓣打压植骨保髋术治疗中青年股骨头坏死(ONFH)的疗效,为避免或推迟中青年股骨头坏死患者全髋关节置换术(THA)寻找一种新的方法。

方法

2006 年 1 月至 2010 年 12 月,我们对 60 例(66 髋)ARCO 分期为Ⅲ期的中青年股骨头坏死患者采用带血管蒂大转子骨瓣复合游离髂骨瓣打压植骨保髋术治疗,术后随访采用 Harris 髋关节评分评价临床疗效,定期拍摄 X 线片进行影像学评估,采用 SF-36 量表评估生活质量。以再次行保髋手术或行 THA 手术作为终末观察时间。

结果

最终电话随访 58 例(64 髋)患者,失访 2 例,随访时间 1260 个月,平均 35.8 个月。患者一般资料为 ARCO ⅢA 期 16 髋,ⅢB 期 22 髋,ⅢC 期 26 髋。术后 X 线片显示股骨头坏死区修复良好,股骨头、髋臼覆盖率改善。末次随访时 Harris 髋关节评分为 86.56±7.38 分(优 87.50%),较术前的 50.95±6.86 分明显提高。SF-36 量表各维度评分也较术前有不同程度的提高。同时,生理机能(PCS)评分由术前的 42±13 分提高至 78±11 分,PCS 评分由术前的 51±10 分提高至 76±11 分,差异均有统计学意义(p=0.005,p=0.01),表明患者的生活质量有明显改善。Harris 髋关节评分与 SF-36 量表各维度呈正相关(r=0.320.72),其中与生理机能(PF)、躯体角色(RP)和躯体疼痛(BP)相关性最强(r=0.72,p<0.01;r=0.58,p<0.01;r=0.65,p<0.01)。

结论

带血管蒂大转子骨瓣复合游离髂骨瓣打压植骨保髋术治疗中青年股骨头坏死疗效确切,重建了股骨头的生物力学稳定性,促进了坏死区的修复,间接保存了中青年股骨头坏死患者的髋关节功能,具有重要的临床和实用价值,能满足患者的基本生活需求,尤其适合中青年股骨头坏死患者,可避免或推迟全髋关节置换术(THA)。

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