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儿童健康最新动态：女婴阴唇粘连用雌激素乳膏。

Child health update: estrogen cream for labial adhesion in girls.

机构信息

BC Children's Hospital, Department of Pediatrics, Room K4-226, Ambulatory Care Bldg, 4480 Oak St, Vancouver, BC V6H 3V4.

出版信息

Can Fam Physician. 2013 Jan;59(1):37-8.

PMID:23341655
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3555651/
Abstract

QUESTION

Should I prescribe estrogen cream to treat labial adhesion in my prepubertal female patients?

ANSWER

Many physicians offer young girls estrogen cream to be applied on the labia for several weeks to treat labial adhesion. While no randomized controlled trial data are available, the success rate of such creams is reported in the literature to be close to 90%. Side effects of estrogen cream are mild and transient. Although the ideal frequency and length of treatment with estrogen cream has yet to be determined, most treatment recommendations suggest application of the cream 1 to 2 times a day; treatment should be applied for a few weeks before considering surgical alternatives.

摘要

问题

我应该给我的青春期前女患者开雌激素乳膏来治疗阴唇粘连吗？

答案

许多医生会给小女孩开雌激素乳膏，让她们在阴唇上涂抹数周来治疗阴唇粘连。虽然目前尚无随机对照试验数据，但文献报道此类乳膏的成功率接近 90%。雌激素乳膏的副作用轻微且短暂。虽然尚未确定使用雌激素乳膏的理想频率和时长，但大多数治疗建议建议每天使用乳膏 1 到 2 次；在考虑手术替代方案之前，应先使用乳膏治疗数周。

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本文引用的文献

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How should we treat prepubertal labial adhesions? Retrospective comparison of topical treatments: estrogen only, betamethasone only, and combination estrogen and betamethasone.
J Pediatr Adolesc Gynecol. 2011 Dec;24(6):389-91. doi: 10.1016/j.jpag.2011.07.015. Epub 2011 Sep 25.
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