Department of Dermatology, Pusan National University School of Medicine, Busan, Korea. ; Biomedical Research Institute, Pusan National University Hospital, Busan, Korea.
J Korean Med Sci. 2013 Jan;28(1):145-51. doi: 10.3346/jkms.2013.28.1.145. Epub 2013 Jan 8.
Tinea incognito (TI) is a dermatophytic infection which has lost its typical clinical appearance because of improper use of steroids or calcineurin inhibitors. The incidence of TI is increasing nowadays. We conducted retrospective review on 283 patients with TI from 25 dermatology training hospitals in Korea from 2002-2010 to investigate the demographical, clinical, and mycological characteristics of TI, and to determine the associated risk factors. More than half (59.3%) patients were previously treated by non-dermatologists or self-treated. The mean duration of TI was 15.0 ± 25.3 months. The most common clinical manifestations were eczema-like lesion, psoriasis-like, and lupus erythematosus-like lesion. The trunk and face were frequently involved, and 91 patients (32.2%) also had coexisting fungal infections. Among 67 isolated strains, Trichophyton rubrum was the most frequently detected (73.1%). This is the largest study of TI reported to date and the first investigational report concerning TI in Korea. We suggest that doctors should consider TI when a patient has intractable eczema-like lesions accompanied by tinea pedis/unguium. Furthermore, there should be a policy change, which would make over-the-counter high-potency topical steroids less accessible in some countries, including Korea.
隐性体癣(TI)是一种皮肤癣菌感染,由于类固醇或钙调磷酸酶抑制剂的不当使用,其典型的临床特征已经消失。如今,TI 的发病率正在上升。我们对 2002 年至 2010 年间韩国 25 家皮肤科培训医院的 283 例 TI 患者进行了回顾性研究,以调查 TI 的人口统计学、临床和真菌学特征,并确定相关的危险因素。超过一半(59.3%)的患者先前由非皮肤科医生治疗或自行治疗。TI 的平均病程为 15.0 ± 25.3 个月。最常见的临床表现为湿疹样病变、银屑病样和红斑狼疮样病变。病变常累及躯干和面部,91 例(32.2%)患者同时存在其他真菌感染。在 67 株分离株中,红色毛癣菌的检出率最高(73.1%)。这是迄今为止报道的最大规模的 TI 研究,也是韩国首例关于 TI 的调查研究报告。我们建议,当患者出现难以治疗的湿疹样病变并伴有足癣/甲癣时,医生应考虑 TI。此外,一些国家,包括韩国,应该改变政策,使某些国家的非处方高浓度外用类固醇更难获得。