伴有Id反应的非典型体癣：一例报告及乌帕替尼成功治疗
Atypical tinea corporis with Id reaction: A case report and successful treatment with upadacitinib.
作者信息
Mao Jing, Tong Zequn, Su Xinhong, Zhuang Zheyu, Bao Siyi, Chen Ying, Xiao Zhixun, Gong Ting, Ji Chao
机构信息
Department of Dermatology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China.
Department of Dermatology, Nanchong Central Hospital, The Second Clinical Medical College of North Sichuan Medical College, Capital Medical University Affiliated Beijing Anzhen Hospital Nan Chong Hospital, Nanchong, Sichuan, China.
出版信息
IDCases. 2025 Jun 21;41:e02300. doi: 10.1016/j.idcr.2025.e02300. eCollection 2025.
Atypical tinea corporis, characterized by clinical manifestations that resemble other skin disorders, can lead to misdiagnosis and delayed treatment. This 67-year-old male had a seven-month history of pruritic skin lesions resembling subcorneal pustular dermatosis. Dermatological exam and fungal culture confirmed -induced atypical tinea corporis. After oral itraconazole treatment, he developed symmetrical eczematous lesions (Id reaction) on his extremities. Initial treatment was ineffective, so upadacitinib was administered, resulting in significant improvement at eight weeks. This case highlights atypical tinea presentations, Id reactions, and introduces upadacitinib as a novel treatment option for refractory Id reactions.
非典型体癣，其临床表现类似于其他皮肤疾病，可导致误诊和治疗延误。这位67岁男性有7个月的瘙痒性皮肤病变病史，类似角层下脓疱性皮肤病。皮肤科检查和真菌培养确诊为诱发的非典型体癣。口服伊曲康唑治疗后，他的四肢出现对称性湿疹样病变（癣菌疹反应）。初始治疗无效，因此给予乌帕替尼治疗，8周时病情显著改善。该病例突出了非典型体癣表现、癣菌疹反应，并介绍了乌帕替尼作为难治性癣菌疹反应的一种新的治疗选择。
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