Institute of Geriatric Cardiology, Chinese PLA General Hospital, Beijing 100853, China ; Department of Geriatric Cardiology, Beijing Military General Hospital, Beijing 100700, China.
J Geriatr Cardiol. 2012 Dec;9(4):361-5. doi: 10.3724/SP.J.1263.2012.10021.
To assess the secular trends in the etiology and comorbidity of patients hospitalized with congestive heart failure (CHF).
Data of 7,319 patients (mean age 59.6 years, 62.1% male) with a primary discharge diagnosis of CHF, hospitalized from January 1, 1993 to December 31, 2007 at the Chinese People's Liberation Army (PLA) General Hospital were extracted and analyzed. These patients were divided into three groups according to hospitalization period: 1993-1997 (n = 1623), 1998-2002 (n = 2444), and 2003-2007 (n = 3252). The etiological characteristics and comorbidities were assessed.
Over the study period, the proportion of patients with ischemic heart disease (IHD) increased from 37.2% during the period 1993-1997 to 46.8% during the period 2003-2007, while that with valvular heart disease (VHD) decreased from 35.2% during the period 1993-1997 to 16.6% during the period 2003-2007 (both P < 0.05). Atrial fibrillation (AF) was the most common comorbidity of heart failure (23.2%, 23.0% and 20.6%, respectively, in the three periods). Compared to that of the period of 1993-1997 with that of, the proportion of patients with myocardial infarction, pneumonia, renal function impairment and hepatic cirrhosis of the period of 2003-2007 increased significantly (P < 0.05) and the proportion of patients with chronic obstructive pulmonary disease and atrial fibrillation decreased significantly (P < 0.05).
This study implies that IHD has became a more common etiology of CHF, while VHD has deceased as an etiology of CHF in Chinese patients during the last two decades.
评估充血性心力衰竭（CHF）住院患者病因和合并症的长期趋势。
提取并分析了 1993 年 1 月 1 日至 2007 年 12 月 31 日在中国人民解放军总医院因首次确诊为 CHF 而住院的 7319 例患者（平均年龄 59.6 岁，62.1%为男性）的数据。根据住院时间将这些患者分为三组：1993-1997 年（n=1623）、1998-2002 年（n=2444）和 2003-2007 年（n=3252）。评估了病因特征和合并症。
在研究期间，缺血性心脏病（IHD）患者的比例从 1993-1997 年期间的 37.2%增加到 2003-2007 年期间的 46.8%，而瓣膜性心脏病（VHD）患者的比例从 1993-1997 年期间的 35.2%下降到 2003-2007 年期间的 16.6%（均 P<0.05）。心房颤动（AF）是心力衰竭最常见的合并症（三个时期分别为 23.2%、23.0%和 20.6%）。与 1993-1997 年相比，2003-2007 年期间心肌梗死、肺炎、肾功能损害和肝硬化患者的比例显著增加（P<0.05），而慢性阻塞性肺疾病和心房颤动患者的比例显著降低（P<0.05）。
本研究表明，在过去二十年中，IHD 已成为 CHF 的更常见病因，而 VHD 已成为 CHF 的病因。
