Drachenberg C B, Papadimitriou J C
Department of Pathology, University of Maryland School of Medicine, Baltimore.
Arch Pathol Lab Med. 1990 May;114(5):463-7.
We describe a patient with a melanotic peritoneal cyst. The multilocular cyst was lined by heavily pigmented mesothelial cells. Scattered dendritic melanocytes were also seen underlying the mesothelium. By light and electron microscopy, the lesion appeared to imitate the pigmentation process of the skin. Special stains, to confirm the character of both mesothelial and dendritic cells (melanocytes), were also performed. The above findings constitute the first complete documentation of the relationship of melanocytes with mesothelial cells in humans. Thus, the possibility of primary melanosis peritonei, independent of melanogenic tumors of the ovary, is shown.
我们描述了一名患有黑色素性腹膜囊肿的患者。这个多房性囊肿内衬有色素沉着严重的间皮细胞。在间皮下方还可见散在的树突状黑素细胞。通过光镜和电镜观察，该病变似乎模仿了皮肤的色素沉着过程。还进行了特殊染色，以确认间皮细胞和树突状细胞（黑素细胞）的特征。上述发现首次完整记录了人类黑素细胞与间皮细胞之间的关系。因此，显示了存在独立于卵巢黑素生成性肿瘤的原发性腹膜黑变病的可能性。
