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印度家庭接触者中结核菌素皮肤试验与全血γ-干扰素释放试验(QFT-TB)在检测潜伏性结核感染方面的一致性

Agreement between skin testing and QuantiFERON-TB Gold In-Tube assay (QFT-TB) in detecting latent tuberculosis infection among household contacts in India.

作者信息

Pattnaik Satyajit, John K R, Shalini E, Michael J S

机构信息

Department of Community Medicine, Kalinga Institute of Medical Sciences (KIMS), KIIT University, Bhubaneswar, Odisha.

出版信息

Indian J Tuberc. 2012 Oct;59(4):214-8.

PMID:23342541
Abstract

AIMS

The present study was designed to find the agreement between Tuberculin Skin Test and interferon gamma assay test in detecting latent tuberculosis infection in household contacts of sputum culture positive tuberculosis cases.

SETTING

Department of Community Medicine, Christian Medical College, Vellore.

METHODS

One hundred and fifty household contacts of sputum culture positive tuberculosis cases were tested with both the methods simultaneously and actual as well as kappa agreement was determined.

RESULTS

The overall actual agreement between both the tests was found to be 82% with a kappa agreement of 0.57.

CONCLUSION

The agreement was very high (both percentage agreement and Kappa) in pediatric contacts but it was poor in adult contacts.

摘要

目的

本研究旨在探讨结核菌素皮肤试验与干扰素γ检测试验在检测痰培养阳性肺结核病例家庭接触者潜伏性结核感染方面的一致性。

地点

韦洛尔基督教医学院社区医学系。

方法

对150例痰培养阳性肺结核病例的家庭接触者同时采用两种方法进行检测,并确定实际一致性和kappa一致性。

结果

两种检测方法的总体实际一致性为82%,kappa一致性为0.57。

结论

在儿童接触者中一致性非常高(百分比一致性和kappa值均如此),但在成人接触者中一致性较差。

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