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[治疗性全身降温在新生儿缺氧缺血性脑病治疗中的应用——波兰首例]

[The use of therapeutic whole body cooling in treating hypoxic-ischemic encephalopathy in the newborn--the first case in Poland].

作者信息

Gadzinowski Janusz, Gulczyńska Ewa, Michniewicz Barbara, Opala Tomasz, Buks Joanna

机构信息

Katedra i Klinika Neonatologii Uniwersytetu Medycznego im. K. Marcinkowskiego w Poznaniu, Polska.

出版信息

Ginekol Pol. 2012 Aug;83(8):630-2.

Abstract

Hypoxic-ischemic encephalopathy (ENN) concerns neonates born after 35 completed weeks of gestation. The incidence rate has been shown to be 1-6/1000 births and can lead to significant permanent neurological damage, cerebral palsy and even death. Until the whole body cooling and selective brain cooling methods have been accepted, the treatment of children with ENN was only symptomatic. The article describes the first case of ENN neonatal treatment with the whole body hypothermia in Poland, which took place at the Department of Neonatology Poznań University of Medical Sciences. Currently both methods--whole body hypothermia and selective brain cooling--offer a chance for a normal neurological development and a better life for children born with ENN. Both methods are accessible in a few centers in Poland.

摘要

缺氧缺血性脑病(ENN)涉及妊娠满35周后出生的新生儿。其发病率已显示为每1000例出生中有1 - 6例,可导致严重的永久性神经损伤、脑瘫甚至死亡。在全身降温及选择性脑降温方法被接受之前,ENN患儿的治疗仅为对症治疗。本文描述了波兰首例在波兹南医科大学新生儿科采用全身低温治疗ENN新生儿的病例。目前,全身低温和选择性脑降温这两种方法都为ENN患儿提供了神经正常发育和更好生活的机会。这两种方法在波兰的少数几个中心都可采用。

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