Obstetrics and Gynaecology Department, Autónoma University of Madrid, Hospital Universitario Puerta de Hierro, Madrid, Spain.
Gynecol Obstet Invest. 2013;75(2):120-5. doi: 10.1159/000345576. Epub 2013 Jan 19.
To determine the efficacy of the angiographic indexes of 3D power Doppler angiography (3D-PDA) for the diagnosis of malignancy in complex ovarian masses.
A prospective, observational study of 72 patients with complex adnexal mass.
In the morphological study, 3D ultrasound showed sensitivity, specificity, PPV, NPV, PLHR and NLHR of 84.6%, 81.9%, 85.1%, 81.8%, 4.65 and 0.19. No differences in vascular indexes (VI, FI, VFI) between malignant and benign masses were found: VI 5.38 (CI 95% 3.06-7.7) vs. 6.29 (CI 95% 4.41-8.17) (p = 0.53); FI 29.6 (CI 95% 25.17-34.08) vs. 33.8 (CI 95% 30.03-37.3) (p = 0.15); VFI 1.68 (CI 95% 0.94-2.42) vs. 2.37 (CI 95% 1.49-3.25) (p = 0.24). When analysed according to different stages, VI was higher in patients with more advanced stages of disease; 4.34 (95% CI 2.21-6.47) vs. 7.38 (95% CI 4.7-10.06) (p = 0.11). FI was significantly lower in patients with early stages of disease; FI 29.07 (95% CI 21.49-36.68) vs. 36.46 (95% CI 32.31-40.62) (p = 0.04). For VFI, differences were not significant, although there was a strong trend; VFI 1.47 (95% CI 0.67-2.28) vs. 2.86 (95% CI 1.57-4.16) (p = 0.11). 3D-PDA indexes were significantly higher in patients with positive adenopathies.
3D-PDA values increase progressively, but not significantly, with the stage of the disease.
确定三维能量多普勒血管造影（3D-PDA）的血管造影指数对复杂卵巢肿块恶性肿瘤的诊断价值。
对 72 例复杂附件肿块患者进行前瞻性、观察性研究。
在形态学研究中，3D 超声显示敏感性、特异性、PPV、NPV、PLHR 和 NLHR 分别为 84.6%、81.9%、85.1%、81.8%、4.65 和 0.19。恶性和良性肿块之间的血管指数（VI、FI、VFI）无差异：VI 5.38（95%CI 95%3.06-7.7）与 6.29（95%CI 95%4.41-8.17）（p=0.53）；FI 29.6（95%CI 95%25.17-34.08）与 33.8（95%CI 95%30.03-37.3）（p=0.15）；VFI 1.68（95%CI 95%0.94-2.42）与 2.37（95%CI 95%1.49-3.25）（p=0.24）。按不同分期分析时，疾病分期较高的患者 VI 较高；4.34（95%CI 2.21-6.47）与 7.38（95%CI 4.7-10.06）（p=0.11）。FI 在疾病早期阶段明显较低；FI 29.07（95%CI 21.49-36.68）与 36.46（95%CI 32.31-40.62）（p=0.04）。对于 VFI，差异虽不显著，但有明显趋势；VFI 1.47（95%CI 0.67-2.28）与 2.86（95%CI 1.57-4.16）（p=0.11）。3D-PDA 指数在有阳性淋巴结病的患者中显著升高。
3D-PDA 值随疾病分期的进展而逐渐升高，但无显著差异。
