Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, New York Presbyterian Hospital-Weill Cornell Medical Center, New York, New York 10021, USA.
Obstet Gynecol. 2013 Feb;121(2 Pt 2 Suppl 1):465-8. doi: 10.1097/aog.0b013e31826d7da6.
Placental site trophoblastic tumor is a rare subtype of gestational trophoblastic neoplasia affecting women of reproductive age. The preferred method of treatment is surgical resection.
A 33-year-old woman, gravida 3 para 1111, was incidentally diagnosed with placental site trophoblastic tumor during an evaluation for infertility. As a result of persistent pathologic evidence of disease, she underwent a hysterectomy. The site of disease on pathologic review of the hysterectomy specimen was widely discordant from the preoperative imaging and hysteroscopic evaluations.
Wedge resection of the uterus has been suggested as an acceptable alternative to hysterectomy in women with placental site trophoblastic tumor who wish to preserve future fertility. However, this case demonstrated that preoperative imaging may not correlate with the tumor site, making wedge resection treatment ineffective.
胎盘部位滋养细胞肿瘤是一种罕见的妊娠滋养细胞肿瘤亚型,影响育龄妇女。首选的治疗方法是手术切除。
一位 33 岁的妇女,孕 3 产 1111,在不孕评估中意外诊断为胎盘部位滋养细胞肿瘤。由于疾病的病理证据持续存在,她接受了子宫切除术。子宫切除术标本的病变部位与术前影像学和宫腔镜检查结果广泛不一致。
对于希望保留未来生育能力的胎盘部位滋养细胞肿瘤妇女,楔形切除术已被建议作为子宫切除术的一种可接受的替代方法。然而,本例表明术前影像学可能与肿瘤部位不相关,使楔形切除术治疗无效。