Cancer Research UK and EPSRC Cancer Imaging Centre, Institute of Cancer Research and Royal Marsden NHS Foundation Trust, DownsRd, Sutton, SM2 5PT, United Kingdom.
AJR Am J Roentgenol. 2013 Feb;200(2):249-60. doi: 10.2214/AJR.12.8932.
Functional MR techniques report on a variety of biologic features of tumors: dynamic contrast-enhanced, diffusion-weighted, and intrinsic susceptibility-weighted MRI and MR spectroscopy reflect, at a simplistic level, vascularity, cellularity, hypoxic status, and metabolism, respectively. This article reviews the evidence for each of the functional MR readouts to determine these clinical end points and thus influence the management of ovarian, endometrial, and cervical cancer.
These techniques may be implemented in gynecologic malignancies to detect, characterize, and stage tumors as well as potentially to predict the outcome and measure response to treatment.
功能磁共振技术报告了肿瘤的多种生物学特征：动态对比增强、扩散加权和内在磁化率加权 MRI 以及磁共振波谱分别反映了血管生成、细胞密度、缺氧状态和代谢水平。本文综述了每种功能磁共振读出技术的证据，以确定这些临床终点，从而影响卵巢癌、子宫内膜癌和宫颈癌的治疗。
这些技术可用于妇科恶性肿瘤的检测、特征描述和分期，以及潜在地预测治疗结果和测量治疗反应。
