DNA转录孤子理论的结果与局限性。
Results and limitations of the soliton theory of DNA transcription.
作者信息
Gaeta G
机构信息
Dipartimento di Fisica, Universitá di Roma, 00185 Roma (, Italy.
出版信息
J Biol Phys. 1999 Jun;24(2-4):81-96. doi: 10.1023/A:1005158503806.
Abstract
It has been suggested by several authors that nonlinear excitations, in particular solitary waves, could play a fundamental functional role in the process of DNA transcription, effecting the opening of the double chain needed for RNA Polymerase to be able to copy the genetic code. Some models have been proposed to model the relevant DNA dynamics in terms of a reduced number of effective degrees of freedom. Here I discuss advantages and disadvantages of such an approach, and discuss in more detail one of the models, i.e. the one proposed by Yakushevich.
摘要
几位作者提出，非线性激发，特别是孤立波，可能在DNA转录过程中发挥基本的功能作用，影响RNA聚合酶复制遗传密码所需的双链打开。已经提出了一些模型，用减少的有效自由度来模拟相关的DNA动力学。在这里，我讨论这种方法的优缺点，并更详细地讨论其中一个模型，即雅库舍维奇提出的模型。
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