Tsyganov M A, Kresteva I B, Aslanidi G V, Aslanidi K B, Deev A A, Ivanitsky G R
Institute for Theoretical and Experimental Biophysics, Pushchino, Moscow region, 1429292 Russia.
J Biol Phys. 1999 Jun;25(2-3):165-76. doi: 10.1023/A:1005153720027.
Three types of population growth and development of chemotaxic motile bacteria Escherichia coli on semi-solid nutrient media are investigated: a) stable development - circular symmetrical waves; b) bursts; c) fractal-like self-organization. Experimental investigation of the burst formation is presented. The microscopic analysis of growing, fractal-like structures is carried out, and a mechanism for such structure formation is suggested. It is supposed that fractal-like bacterial structures growth is based on the principle of successively forming multiple micro-bursts. A mathematical model has been suggested to reproduce the experimental results. The structures obtained by numerical modeling of population growth in the parameter space 'substrate concentration - bacterial movement rate' reproduce the corresponding experimental structures in the space 'nutrient concentration in the media - the density of the media'.
a）稳定发育——圆形对称波；b）爆发；c）类分形自组织。给出了爆发形成的实验研究。对生长的类分形结构进行了微观分析，并提出了这种结构形成的机制。据推测，类分形细菌结构的生长基于连续形成多个微爆发的原理。已提出一个数学模型来重现实验结果。通过在“底物浓度-细菌运动速率”参数空间中对群体生长进行数值模拟得到的结构，在“培养基中的营养浓度-培养基密度”空间中重现了相应的实验结构。
