Thavorncharoensap Montarat, Teerawattananon Yot, Natanant Sirin, Kulpeng Wantanee, Yothasamut Jomkwan, Werayingyong Pitsaphun
Department of Pharmacy, Faculty of Pharmacy, Mahidol University, Thailand ; Health Intervention and Technology Assessment Program (HITAP), Ministry of Public Health, Thailand.
Clinicoecon Outcomes Res. 2013;5:29-36. doi: 10.2147/CEOR.S38062. Epub 2013 Jan 9.
This study aims to elicit the value of the willingness to pay (WTP) for a quality-adjusted life year (QALY) and to examine the factors associated with the WTP for a QALY (WTP/QALY) value under the Thai health care setting.
A community-based survey was conducted among 1191 randomly selected respondents. Each respondent was interviewed face-to-face to elicit his/her health state preference in each of three pairs of health conditions: (1) unilateral and bilateral blindness, (2) paraplegia and quadriplegia, and (3) mild and moderate allergies. A visual analog scale (VAS) and time trade off (TTO) were used as the eliciting methods. Subsequently, the respondents were asked about their WTP for the treatment and prevention of each pair of health conditions by using a bidding-game technique.
With regards to treatment, the mean WTP for a QALY value (WTP/QALY(treatment)) estimated by the TTO method ranged from 59,000 to 285,000 baht (16.49 baht = US$1 purchasing power parity [PPP]). In contrast, the mean WTP for a QALY value in terms of prevention (WTP/QALY(prevention)) was significantly lower, ranging from 26,000 to 137,000 baht. Gender, household income, and hypothetical scenarios were also significant factors associated with the WTP/QALY values.
The WTP/QALY values elicited in this study were approximately 0.4 to 2 times Thailand's 2008 GDP per capita. These values were in line with previous studies conducted in several different settings. This study's findings clearly support the opinion that a single ceiling threshold should not be used for the resource allocation of all types of interventions.
本研究旨在得出质量调整生命年(QALY)的支付意愿(WTP)值,并考察泰国医疗保健环境下与QALY支付意愿(WTP/QALY)值相关的因素。
对1191名随机抽取的受访者进行了一项基于社区的调查。每位受访者都接受了面对面访谈,以了解其在三对健康状况中的每一对中的健康状态偏好:(1)单眼失明和双眼失明,(2)截瘫和四肢瘫,以及(3)轻度和中度过敏。采用视觉模拟量表(VAS)和时间权衡法(TTO)作为获取偏好的方法。随后,通过投标博弈技术询问受访者对每对健康状况的治疗和预防的支付意愿。
在治疗方面,通过TTO方法估计的QALY值的平均支付意愿(WTP/QALY(治疗))范围为59,000至285,000泰铢(16.49泰铢 = 1美元购买力平价[PPP])。相比之下,预防方面的QALY值的平均支付意愿(WTP/QALY(预防))显著较低,范围为26,000至137,000泰铢。性别、家庭收入和假设情景也是与WTP/QALY值相关的重要因素。
本研究得出的WTP/QALY值约为泰国2008年人均国内生产总值的0.4至2倍。这些值与先前在几个不同环境中进行的研究一致。本研究的结果明确支持以下观点,即不应将单一的上限阈值用于所有类型干预措施的资源分配。