Doyle Laura, Hesney Adam J, Chapman Katherine L, Liu Haisong, Weiner Perry R, Dicker Adam P, Yu Yan, Showalter Timothy N
Department of Radiation Oncology, Jefferson Medical College of Thomas Jefferson University, Kimmel Cancer Center, Philadelphia.
J Contemp Brachytherapy. 2012 Sep;4(3):176-81. doi: 10.5114/jcb.2012.30684. Epub 2012 Sep 29.
Post-implant dosimetry following prostate seed implantation (PSI) occasionally reveals suboptimal dosimetric coverage of the gland. Published reports of re-implantation techniques have focused on earlier-generation techniques, including preplanned approaches and stranded seeds. The purpose of this case report is to describe a customizable approach to perform corrective re-implantation using loose seeds and intraoperative planning technique.
This case report describes a 63-year-old male with favorable risk prostate adenocarcinoma receiving PSI. Thirty day post-implant dosimetric evaluation revealed suboptimal coverage of the base of the gland. Using guidance from post-implant CT-images and real-time planning, the patient received a corrective re-implantation with intraoperative planning.
Post-implant dosimetry after re-implantation procedure with intraoperative planning yielded improved target volume coverage that achieved standard dosimetric criteria.
Re-implantation as a salvage treatment technique after sub-optimal PSI is a valid treatment option performed with intraoperative real-time planning.
前列腺籽源植入术(PSI)后的植入后剂量测定偶尔会显示腺体的剂量覆盖不理想。已发表的再植入技术报告主要集中在早期技术,包括预先计划的方法和滞留籽源。本病例报告的目的是描述一种使用松散籽源和术中计划技术进行矫正性再植入的可定制方法。
本病例报告描述了一名63岁低危前列腺腺癌男性接受PSI。植入后30天的剂量测定评估显示腺体底部覆盖不理想。利用植入后CT图像的引导和实时计划,患者接受了术中计划的矫正性再植入。
术中计划的再植入手术后的植入后剂量测定显示靶体积覆盖得到改善,达到了标准剂量标准。
作为次优PSI后的挽救治疗技术,再植入是一种通过术中实时计划进行的有效治疗选择。