Mostafa S M, Wiles J R, Dowd T, Bates R, Bricker S
Department of Anaesthesia, Royal Liverpool Hospital.
Br J Anaesth. 1990 Apr;64(4):515-7. doi: 10.1093/bja/64.4.515.
We have examined the effect of preoperative administration of nebulized lignocaine or saline on the intraocular pressure (IOP) response to tracheal intubation in 20 adults. In the saline group, tracheal intubation was associated with a significant increase in IOP above control and preintubation values (P less than 0.01); in the lignocaine group there was no change in IOP following intubation. After intubation, IOP was significantly less in the lignocaine group than in the saline group (P less than 0.05).
我们研究了雾化利多卡因或生理盐水术前给药对20名成年人气管插管后眼压（IOP）反应的影响。在生理盐水组中，气管插管与眼压显著高于对照值和插管前值相关（P<0.01）；在利多卡因组中，插管后眼压没有变化。插管后，利多卡因组的眼压显著低于生理盐水组（P<0.05）。
