交界性卵巢肿瘤的全球组织学分布：一项系统评价。
Histologic distribution of borderline ovarian tumors worldwide: a systematic review.
机构信息
Department of Obstetrics and Gynecology, CHA Gangnam Medical Center, CHA University, Seoul, Korea.
出版信息
J Gynecol Oncol. 2013 Jan;24(1):44-51. doi: 10.3802/jgo.2013.24.1.44. Epub 2013 Jan 8.
OBJECTIVE
The histologic types of borderline ovarian tumors (BOTs) exhibit striking differences in clinical behavior and prognosis. Yet, there is no information available on the histologic distribution of BOTs according to geographic region. The purpose of this study was to systematically review this issue worldwide.
METHODS
A comprehensive search of the literature was conducted using electronic databases. Studies were eligible if BOTs were investigated and the histologic distribution of the data was shown. The studies were grouped by geographic region and totaled by country.
RESULTS
Of 487 potentially relevant studies, 51 met our inclusion criteria, as follows: 8 studies from North America (2 countries); 26 studies from Europe (14 countries); 7 studies from the Middle East (3 countries); and 10 studies from East Asia (5 countries). The histologic distribution of BOTs was considerably different in different parts of the world, but follows specific patterns. In general, serous-type BOTs were the predominantly identified histology in North America, the Middle East, and Europe, while mucinous-type BOTs predominated in East Asia.
CONCLUSION
Significant geographic variation is evident among BOT histology in different parts of the world. More research is needed to understand this phenomenon.
目的
交界性卵巢肿瘤（BOT）的组织学类型在临床行为和预后方面存在显著差异。然而，目前尚无关于 BOT 组织学分布的地理区域信息。本研究的目的是在全球范围内系统地回顾这个问题。
方法
使用电子数据库进行了全面的文献检索。如果研究中调查了 BOT 并显示了数据的组织学分布，则符合纳入标准。研究按地理区域分组，并按国家进行汇总。
结果
在 487 篇潜在相关研究中，有 51 篇符合纳入标准，如下所示：北美（2 个国家）的 8 项研究；欧洲（14 个国家）的 26 项研究；中东（3 个国家）的 7 项研究；东亚（5 个国家）的 10 项研究。BOT 的组织学分布在世界不同地区存在显著差异，但遵循特定模式。一般来说，在北美、中东和欧洲，浆液型 BOT 是主要的组织学类型，而黏液型 BOT 则在东亚占主导地位。
结论
在世界不同地区，BOT 的组织学存在明显的地理差异。需要进一步研究以了解这种现象。
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