Na Eun Duc, Cha Dong Hyun, Cho Jung Hyun, Kim Mi Kyoung
Department of Obstetrics and Gynecology, CHA Gangnam Medical Center, CHA University, Seoul, Korea.
Clin Exp Reprod Med. 2012 Dec;39(4):182-6. doi: 10.5653/cerm.2012.39.4.182. Epub 2012 Dec 31.
Many studies have demonstrated that hydrosalpinx has a detrimental effect on the outcome of IVF. Treating hydrosalpinges prior to the IVF procedure in women with hydrosalpinges is thought to improve the likelihood of successful IVF outcome. Vaginal ultrasound-guided aspiration of hydrosalpinx fluid (HSF) with injection of the sclerosing agent in situ might be simpler than invasive procedures like salpingectomy. Therefore, we carried out a retrospective study on the effects of ultrasound-guided HSF aspiration and injection of the sclerosing agent of ultrasonically diagnosed hydrosalpinx on IVF outcome.
In our retrospective study, 97 tubal factor infertile female patients that underwent IVF treatment between January 2005 and December 2012 at the Reproductive Medicine Center of CHA Hospital were divided into two study groups. Fifty-six patients underwent interventional ultrasound sclerotherapy (group 1), and the remaining 41 patients received laparoscopic salpingectomy (group 2) before IVF. We compared the IVF outcomes of the two groups.
The results showed that ultrasound-guided HSF aspiration and sclerotherapy have IVF outcomes comparable to laparoscopic salpingectomy.
Interventional ultrasound guided sclerotherapy before IVF is an effective and less invasive prophylactic intervention alternative to salpingectomy with hydrosalpinx.
许多研究表明，输卵管积水对体外受精（IVF）结局有不利影响。对于患有输卵管积水的女性，在IVF手术前治疗输卵管积水被认为可提高IVF成功的可能性。阴道超声引导下抽吸输卵管积水液（HSF）并原位注射硬化剂可能比输卵管切除术等侵入性手术更简单。因此，我们对超声引导下HSF抽吸及注射硬化剂治疗超声诊断的输卵管积水对IVF结局的影响进行了一项回顾性研究。
在我们的回顾性研究中，2005年1月至2012年12月期间在CHA医院生殖医学中心接受IVF治疗的97例输卵管因素不孕女性患者被分为两个研究组。56例患者接受介入性超声硬化治疗（第1组），其余41例患者在IVF前接受腹腔镜输卵管切除术（第2组）。我们比较了两组的IVF结局。
结果显示，超声引导下HSF抽吸及硬化治疗的IVF结局与腹腔镜输卵管切除术相当。
IVF前介入性超声引导硬化治疗是一种有效且侵入性较小的预防性干预方法，可替代输卵管积水的输卵管切除术。
