Yammine Luba, Frazier Lorraine
School of Nursing, The University of Texas Health Science Center at Houston, Houston, Texas, USA.
J Am Assoc Nurse Pract. 2013 Feb;25(2):103-8. doi: 10.1111/j.1745-7599.2012.00779.x. Epub 2012 Sep 24.
The aim of this study was to examine the differences in demographic, psychosocial (depression), and clinical profiles among younger (males ≤ 50 years of age and females ≤ 55 years of age) and older (males > 50 years of age and females > 55 years of age) patients with acute coronary syndrome (ACS).
This study is a preliminary analysis of data collected from 1140 patients with ACS enrolled in an ongoing longitudinal investigation.
As compared to their older counterparts, younger ACS patients were significantly more likely to be obese (p < .001), to smoke (p < .001), to have a higher BDI-II depression score (p < .001), and to feel depressed in the last year (p < .001). In contrast, younger ACS patients were significantly less likely to be dyslipidemic (p < .001), diabetic (p = 0.025), or hypertensive (p < .001) than their older counterparts.
Clinicians need to be persistent in promoting the importance of weight loss and smoking cessation. Screening and treating depression in younger persons is a prudent approach. The significance of regular screening and aggressive treatment of other risk factors (i.e., diabetes, hypertension, and dyslipidemia) should not be overlooked.
本研究旨在探讨年轻(男性≤50岁,女性≤55岁)和年长(男性>50岁,女性>55岁)急性冠状动脉综合征(ACS)患者在人口统计学、心理社会因素(抑郁)和临床特征方面的差异。
本研究是对正在进行的一项纵向调查中纳入的1140例ACS患者所收集数据的初步分析。
与年长的ACS患者相比,年轻的ACS患者明显更易肥胖(p <.001)、吸烟(p <.001)、BDI-II抑郁评分更高(p <.001),且在过去一年中感到抑郁(p <.001)。相比之下,年轻的ACS患者血脂异常(p <.001)、患糖尿病(p = 0.025)或高血压(p <.001)的可能性明显低于年长患者。
临床医生需要持续宣传减肥和戒烟的重要性。对年轻人进行抑郁筛查和治疗是一种审慎的做法。不应忽视定期筛查和积极治疗其他危险因素(即糖尿病、高血压和血脂异常)的重要性。