de Souza Fernando Henrique Carlos, Barros Thiago Bitar Moraes, de Moraes Mariana Teichner, Missumi Larissa Sayuri, Lima Fabiana Roberto, Levy-Neto Mauricio, Shinjo Samuel Katsuyuki
Médicos assistentes do Serviço de Reumatologia do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (FMUSP), São Paulo.
Acta Reumatol Port. 2012 Jul-Sep;37(3):264-7.
The association between autoimmune hepatitis and idiopathic inflammatory myopathies has been rarely described in literature. To our knowledge, there are only five reports of autoimmune hepatitis, all coursing with polymyositis. In the present work, we describe a female patient at the age of 58 with cutaneous lesions (heliotrope), progressive proximal muscle weakness of four limbs and constitutional symptoms for 12 months, and worsened two months ago. She had also been episodes of jaundice for five months. During hospitalization, after intense clinical investigation, the diagnosis of dermatomyositis and autoimmune hepatitis were defined, and the patient had a good clinical and laboratory response to corticosteroids and immunosuppressive.
自身免疫性肝炎与特发性炎性肌病之间的关联在文献中鲜有描述。据我们所知，仅有五例自身免疫性肝炎的报告，均伴有多发性肌炎。在本研究中，我们描述了一名58岁女性患者，有皮肤病变（向阳疹）、四肢进行性近端肌无力及全身症状达12个月，且在两个月前病情加重。她还出现黄疸达五个月。住院期间，经过深入临床检查，确诊为皮肌炎和自身免疫性肝炎，患者对皮质类固醇和免疫抑制剂有良好的临床及实验室反应。
