Siniscalchi Enrico Nastro, Catalfamo Luciano, Allegra Alessandro, Musolino Caterina, De Ponte Francesco Saverio
Unit of Maxillo-Facial Surgery, University of Messina, Azienda, Italy.
J Craniofac Surg. 2013 Jan;24(1):e1-2. doi: 10.1097/SCS.0b013e31826d07b9.
Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a rare but potentially severe condition, and the etiopathology and risk factors are poorly defined. The American Association of Oral and Maxillofacial Surgeons position paper on BRONJ update 2009 remarks all the risk factors of developing BRONJ. Local anatomy such as lingual tori, mylohyoid ridge or palatal tori, and areas with thin mucosa overlying bony prominences represent some of these local factors. We have recently treated a patient presenting a mandibular osteonecrosis involving a rigid miniplate which had been placed 18 years ago during a surgical excision of a radicular cyst. The patient, a 70-year-old female, did not show any other risk factors which could expose her to BRONJ, such as cortisone therapy, head and neck radiotherapy, chemotherapy, periodontal disease, or other.
双膦酸盐相关颌骨坏死(BRONJ)是一种罕见但可能严重的病症,其病因病理和风险因素尚不明确。美国口腔颌面外科医师协会2009年关于BRONJ更新的立场文件阐述了发生BRONJ的所有风险因素。诸如舌隆突、下颌舌骨嵴或腭隆突等局部解剖结构,以及覆盖骨突的黏膜较薄的区域,都是其中一些局部因素。我们最近治疗了一名患者,该患者出现下颌骨坏死,坏死部位涉及一块坚固的微型钢板,该钢板于18年前在根尖囊肿手术切除时放置。患者为一名70岁女性,未表现出任何其他可能使其易患BRONJ的风险因素,如皮质激素治疗、头颈部放疗、化疗、牙周病等。