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经角膜移植术后散光的定制型环曲面人工晶状体植入术。

Implantation of a customized toric intraocular lens for correction of post-keratoplasty astigmatism.

机构信息

Department of Ophthalmology, University Hospital Ayr, Ayr, Scotland, UK.

出版信息

Eye (Lond). 2013 Apr;27(4):531-7. doi: 10.1038/eye.2012.300. Epub 2013 Jan 25.

Abstract

PURPOSE

To report visual and refractive outcomes, and endothelial cell loss following primary and secondary 'piggyback' toric intraocular lens (IOL) implantation in patients with high post-penetrating keratoplasty (PK) astigmatism.

METHODS

Prospective case series. Nine eyes of nine patients with post-PK astigmatism were consecutively recruited for implantation of a customized toric IOL. Six underwent simultaneous phacoemulsification (PE) and three pseudophakic eyes had a secondary 'piggyback' toric IOL implanted in the ciliary sulcus. Mean follow-up time was 17.2±7.7 months. Pre- and post-operative uncorrected (UDVA) and best-corrected (BDVA) distance visual acuities and refractive errors were collected for comparison. Cartesian astigmatic vectors were calculated to identify a change in the magnitude of astigmatism pre- compared to postoperatively. Pre- and post-operative endothelial cell counts were also collected for analysis.

RESULTS

UDVA (logMAR) improved from 1.13±0.51 preoperatively to 0.48±0.24 postoperatively (P-value=0.003). There was no significant change in BDVA (P-value=0.905) from 0.31±0.27 to 0.26±0.19. Corneal astigmatism preoperatively was 6.57±4.40 diopters (D). Post-operative refractive cylinder was 0.83±1.09 D compared to 3.89±4.01 D preoperatively (P=0.039). Analysis of astigmatic Cartesian x and y coordinates found a significant reduction postoperatively compared to preoperatively (P=0.005 and P=0.002), respectively. Mean endothelial cell loss was 9.9%.

CONCLUSION

Implantation of a customized primary or secondary 'piggyback' toric IOL serves as an effective modality in treating patients with high post-PK astigmatism.

摘要

目的

报告在穿透性角膜移植(PK)术后高散光患者中,行原发性和继发性“搭便车”(piggyback)矫正散光的人工晶状体(IOL)植入术后的视力和屈光结果,以及角膜内皮细胞丢失情况。

方法

前瞻性病例系列研究。连续招募 9 例 PK 术后散光患者的 9 只眼,行定制矫正散光的 IOL 植入术。其中 6 只眼同时行超声乳化白内障吸除术(PE),3 只眼行无晶状体眼行二次“搭便车”式的后房型矫正散光 IOL 植入术。平均随访时间为 17.2±7.7 个月。收集比较术前和术后的未矫正(UDVA)和最佳矫正(BDVA)远视力和屈光不正。计算笛卡尔散光矢量以确定术前与术后散光程度的变化。还收集了术前和术后的角膜内皮细胞计数进行分析。

结果

UDVA(logMAR)从术前的 1.13±0.51 提高到术后的 0.48±0.24(P 值=0.003)。BDVA(P 值=0.905)从术前的 0.31±0.27 到术后的 0.26±0.19 没有显著变化。术前角膜散光为 6.57±4.40 屈光度(D)。术后的屈光性散光柱为 0.83±1.09 D,与术前的 3.89±4.01 D 相比(P=0.039)。分析散光笛卡尔 x 和 y 坐标发现术后与术前相比有显著降低(P=0.005 和 P=0.002)。平均角膜内皮细胞丢失率为 9.9%。

结论

植入定制的原发性或继发性“搭便车”矫正散光的 IOL 是治疗 PK 术后高散光患者的有效方法。

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