Department of Ophthalmology, University Hospital Ayr, Ayr, Scotland, UK.
Eye (Lond). 2013 Apr;27(4):531-7. doi: 10.1038/eye.2012.300. Epub 2013 Jan 25.
To report visual and refractive outcomes, and endothelial cell loss following primary and secondary 'piggyback' toric intraocular lens (IOL) implantation in patients with high post-penetrating keratoplasty (PK) astigmatism.
Prospective case series. Nine eyes of nine patients with post-PK astigmatism were consecutively recruited for implantation of a customized toric IOL. Six underwent simultaneous phacoemulsification (PE) and three pseudophakic eyes had a secondary 'piggyback' toric IOL implanted in the ciliary sulcus. Mean follow-up time was 17.2±7.7 months. Pre- and post-operative uncorrected (UDVA) and best-corrected (BDVA) distance visual acuities and refractive errors were collected for comparison. Cartesian astigmatic vectors were calculated to identify a change in the magnitude of astigmatism pre- compared to postoperatively. Pre- and post-operative endothelial cell counts were also collected for analysis.
UDVA (logMAR) improved from 1.13±0.51 preoperatively to 0.48±0.24 postoperatively (P-value=0.003). There was no significant change in BDVA (P-value=0.905) from 0.31±0.27 to 0.26±0.19. Corneal astigmatism preoperatively was 6.57±4.40 diopters (D). Post-operative refractive cylinder was 0.83±1.09 D compared to 3.89±4.01 D preoperatively (P=0.039). Analysis of astigmatic Cartesian x and y coordinates found a significant reduction postoperatively compared to preoperatively (P=0.005 and P=0.002), respectively. Mean endothelial cell loss was 9.9%.
Implantation of a customized primary or secondary 'piggyback' toric IOL serves as an effective modality in treating patients with high post-PK astigmatism.
报告在穿透性角膜移植(PK)术后高散光患者中,行原发性和继发性“搭便车”(piggyback)矫正散光的人工晶状体(IOL)植入术后的视力和屈光结果,以及角膜内皮细胞丢失情况。
前瞻性病例系列研究。连续招募 9 例 PK 术后散光患者的 9 只眼,行定制矫正散光的 IOL 植入术。其中 6 只眼同时行超声乳化白内障吸除术(PE),3 只眼行无晶状体眼行二次“搭便车”式的后房型矫正散光 IOL 植入术。平均随访时间为 17.2±7.7 个月。收集比较术前和术后的未矫正(UDVA)和最佳矫正(BDVA)远视力和屈光不正。计算笛卡尔散光矢量以确定术前与术后散光程度的变化。还收集了术前和术后的角膜内皮细胞计数进行分析。
UDVA(logMAR)从术前的 1.13±0.51 提高到术后的 0.48±0.24(P 值=0.003)。BDVA(P 值=0.905)从术前的 0.31±0.27 到术后的 0.26±0.19 没有显著变化。术前角膜散光为 6.57±4.40 屈光度(D)。术后的屈光性散光柱为 0.83±1.09 D,与术前的 3.89±4.01 D 相比(P=0.039)。分析散光笛卡尔 x 和 y 坐标发现术后与术前相比有显著降低(P=0.005 和 P=0.002)。平均角膜内皮细胞丢失率为 9.9%。
植入定制的原发性或继发性“搭便车”矫正散光的 IOL 是治疗 PK 术后高散光患者的有效方法。